Matches in SemOpenAlex for { <https://semopenalex.org/work/W2933531389> ?p ?o ?g. }
- W2933531389 endingPage "446" @default.
- W2933531389 startingPage "435" @default.
- W2933531389 abstract "Dracocephalum kotschyi Boiss. is one of the important threatened traditional species of medicinal herbs; last pharmaceutical research has shown that rosmarinic acid (RA) and methoxylated flavonoids, particularly, xanthomicrol and cirsimaritin of this plant have anti-cancer, anti-spasm and anti-platelet properties. In this study, Hairy roots were derived from four-week-old leaves inoculated with Agrobacterium rhizogenes strain ATCC15834. The influence of various silicon dioxide nanoparticles (SiO2 NPs) concentrations at two exposure time (24 and 48 h) on growth, antioxidant enzyme capacity, total phenols and flavonoids content (TPC and TFC) and some biochemical traits were investigated. The expression of phenylalanine ammonia-lyase (pal) and rosmarinic acid synthase (ras) genes expression in RA biosynthetic pathway were quantified. The biomass of cultures has substantially by elicitation raised in comparison with control. The activity of antioxidant enzymes, TPC and TFC were impressed by the concentration and duration of treatment. The high RA content (1016.6 μg/g FW) with 8.26-fold increase compared to control, was observed in hairy roots culture elicited with SiO2 NPs (100 mg/L) after 48 h exposure time. The pal and ras genes expression rate in this elicitor concentration and exposure time enhanced notably. Anticancer flavonoids including xanthomicrol, cirsimaritin and isokaempferide showed 13, 13.42 and 10-fold increases compared to the control respectively. Stimulation of D. kotschyi hairy roots by SiO2 NPs caused huge increase in induction and production of important pharmaceutical compounds such as rosmarinic acid and xantomicrol." @default.
- W2933531389 created "2019-04-11" @default.
- W2933531389 creator A5009027936 @default.
- W2933531389 creator A5015855238 @default.
- W2933531389 creator A5049427832 @default.
- W2933531389 creator A5064669648 @default.
- W2933531389 date "2019-07-01" @default.
- W2933531389 modified "2023-10-01" @default.
- W2933531389 title "Pharmaceutical important phenolic compounds overproduction and gene expression analysis in Dracocephalum kotschyi hairy roots elicited by SiO2 nanoparticles" @default.
- W2933531389 cites W1447095829 @default.
- W2933531389 cites W1481584340 @default.
- W2933531389 cites W1559903407 @default.
- W2933531389 cites W1600545176 @default.
- W2933531389 cites W1881073666 @default.
- W2933531389 cites W1913092740 @default.
- W2933531389 cites W1940470282 @default.
- W2933531389 cites W1943327251 @default.
- W2933531389 cites W1965555893 @default.
- W2933531389 cites W1966763345 @default.
- W2933531389 cites W1967444577 @default.
- W2933531389 cites W1970468941 @default.
- W2933531389 cites W1971038644 @default.
- W2933531389 cites W1973146663 @default.
- W2933531389 cites W1975490049 @default.
- W2933531389 cites W1977025217 @default.
- W2933531389 cites W1977099846 @default.
- W2933531389 cites W1984713055 @default.
- W2933531389 cites W1986299796 @default.
- W2933531389 cites W1988621123 @default.
- W2933531389 cites W1990251004 @default.
- W2933531389 cites W1992538565 @default.
- W2933531389 cites W1992594494 @default.
- W2933531389 cites W1993528119 @default.
- W2933531389 cites W1995203863 @default.
- W2933531389 cites W2000288523 @default.
- W2933531389 cites W2001467007 @default.
- W2933531389 cites W2001713684 @default.
- W2933531389 cites W2003014161 @default.
- W2933531389 cites W2011999342 @default.
- W2933531389 cites W2012300645 @default.
- W2933531389 cites W2013494070 @default.
- W2933531389 cites W2020171378 @default.
- W2933531389 cites W2021287724 @default.
- W2933531389 cites W2024556021 @default.
- W2933531389 cites W2026893536 @default.
- W2933531389 cites W2028547186 @default.
- W2933531389 cites W2033748837 @default.
- W2933531389 cites W2033949014 @default.
- W2933531389 cites W2036234818 @default.
- W2933531389 cites W2036787608 @default.
- W2933531389 cites W2037434755 @default.
- W2933531389 cites W2040899136 @default.
- W2933531389 cites W2044355497 @default.
- W2933531389 cites W2048553024 @default.
- W2933531389 cites W2050035169 @default.
- W2933531389 cites W2051341055 @default.
- W2933531389 cites W2059059083 @default.
- W2933531389 cites W2066248621 @default.
- W2933531389 cites W2066300413 @default.
- W2933531389 cites W2072821756 @default.
- W2933531389 cites W2075964201 @default.
- W2933531389 cites W2082028520 @default.
- W2933531389 cites W2087242926 @default.
- W2933531389 cites W2091474030 @default.
- W2933531389 cites W2093330235 @default.
- W2933531389 cites W2093966833 @default.
- W2933531389 cites W2102476539 @default.
- W2933531389 cites W2105922265 @default.
- W2933531389 cites W2107473789 @default.
- W2933531389 cites W2125545268 @default.
- W2933531389 cites W2132072835 @default.
- W2933531389 cites W2133218119 @default.
- W2933531389 cites W2134968156 @default.
- W2933531389 cites W2142642721 @default.
- W2933531389 cites W2155656760 @default.
- W2933531389 cites W2165189049 @default.
- W2933531389 cites W2171549194 @default.
- W2933531389 cites W2174470053 @default.
- W2933531389 cites W2265382277 @default.
- W2933531389 cites W2302427826 @default.
- W2933531389 cites W2317772635 @default.
- W2933531389 cites W2322982665 @default.
- W2933531389 cites W2330724261 @default.
- W2933531389 cites W2547788349 @default.
- W2933531389 cites W2604721361 @default.
- W2933531389 doi "https://doi.org/10.1016/j.indcrop.2019.03.053" @default.
- W2933531389 hasPublicationYear "2019" @default.
- W2933531389 type Work @default.
- W2933531389 sameAs 2933531389 @default.
- W2933531389 citedByCount "54" @default.
- W2933531389 countsByYear W29335313892019 @default.
- W2933531389 countsByYear W29335313892020 @default.
- W2933531389 countsByYear W29335313892021 @default.
- W2933531389 countsByYear W29335313892022 @default.
- W2933531389 countsByYear W29335313892023 @default.
- W2933531389 crossrefType "journal-article" @default.
- W2933531389 hasAuthorship W2933531389A5009027936 @default.
- W2933531389 hasAuthorship W2933531389A5015855238 @default.