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- W2933989969 abstract "A new cystine-glutamate exchanger inhibitor was created through the development of a new catalytic asymmetric synthesis method. Rh-catalyzed catalytic asymmetric hydrogenation of dehydro amino acid esters was expanded to the synthesis of chiral amino acid esters with bis-carbamate protection. The new chemistry was successfully applied to the synthesis of N-benzoyl diamino suberic acid, which showed potent inhibitory effects for cystine-glutamate exchangers, a promising molecular target for cancer therapy. More information can be found in the Communication by T. Shinada et al. on page 5145." @default.
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- W2933989969 date "2019-03-15" @default.
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- W2933989969 title "Front Cover: Catalytic Asymmetric Hydrogenation of Dehydroamino Acid Esters with Biscarbamate Protection and Its Application to the Synthesis of xCT Inhibitors (Chem. Eur. J. 20/2019)" @default.
- W2933989969 doi "https://doi.org/10.1002/chem.201900941" @default.
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