Matches in SemOpenAlex for { <https://semopenalex.org/work/W2936187034> ?p ?o ?g. }
- W2936187034 endingPage "126" @default.
- W2936187034 startingPage "118" @default.
- W2936187034 abstract "Tissue-engineered three-dimensional (3D) scaffolds are required to have a suitable degradation period and biocompatibility. Polyhedral oligomeric silsesquioxane−poly(ethylene glycol) (POSS−PEG) hybrid hydrogels with different degradation rates were prepared by varying the proportion of two cross-linkers, namely degradable PEG-diester-dithiol and non-degradable PEG-dithiol. These hydrogels were used as 3D scaffolds for the encapsulation, culture, and differentiation of cells to elucidate the effects of material biodegradability on cell behavior. Human umbilical vein endothelial cells (HUVECs) encapsulated in the 3D hybrid hydrogels were round-shaped with a cell survival rate of 98%. As the content of degradable cross-linker in the hybrid hydrogels was increased, the number of cells increased more rapidly, and the cell morphology gradually changed from slender spindle to round. Bone marrow mesenchymal stem cells (BMSCs) encapsulated in the 3D hybrid hydrogels grew and proliferated in both osteogenic differentiation media and cell culture growth media. As the content of the degradable cross-linker was increased, the osteogenic differentiation gradually increased, as indicated by the presence of calcium nodes. These results demonstrate that the degradation rates of the hybrid hydrogels had an effect on cell compatibility, morphology, and differentiation." @default.
- W2936187034 created "2019-04-25" @default.
- W2936187034 creator A5002415075 @default.
- W2936187034 creator A5016206959 @default.
- W2936187034 creator A5019014198 @default.
- W2936187034 creator A5029504527 @default.
- W2936187034 creator A5040199434 @default.
- W2936187034 creator A5046311080 @default.
- W2936187034 creator A5057107318 @default.
- W2936187034 creator A5062754890 @default.
- W2936187034 creator A5068039406 @default.
- W2936187034 creator A5075702553 @default.
- W2936187034 date "2019-06-01" @default.
- W2936187034 modified "2023-10-16" @default.
- W2936187034 title "Bioengineered three-dimensional scaffolds to elucidate the effects of material biodegradability on cell behavior using POSS-PEG hybrid hydrogels" @default.
- W2936187034 cites W1963753820 @default.
- W2936187034 cites W1964681850 @default.
- W2936187034 cites W1983554262 @default.
- W2936187034 cites W1989362897 @default.
- W2936187034 cites W2021550972 @default.
- W2936187034 cites W2043022058 @default.
- W2936187034 cites W2043883870 @default.
- W2936187034 cites W2068060413 @default.
- W2936187034 cites W2069183226 @default.
- W2936187034 cites W2070698016 @default.
- W2936187034 cites W2074258313 @default.
- W2936187034 cites W2076911232 @default.
- W2936187034 cites W2077718052 @default.
- W2936187034 cites W2122538859 @default.
- W2936187034 cites W2164840927 @default.
- W2936187034 cites W2168584106 @default.
- W2936187034 cites W2170630067 @default.
- W2936187034 cites W2206196092 @default.
- W2936187034 cites W2206566369 @default.
- W2936187034 cites W2338887251 @default.
- W2936187034 cites W2343552248 @default.
- W2936187034 cites W2346533127 @default.
- W2936187034 cites W2400798143 @default.
- W2936187034 cites W2415992638 @default.
- W2936187034 cites W2537562683 @default.
- W2936187034 cites W2565771368 @default.
- W2936187034 cites W2621281518 @default.
- W2936187034 cites W2686304512 @default.
- W2936187034 cites W2733262158 @default.
- W2936187034 cites W2755747415 @default.
- W2936187034 cites W2766779518 @default.
- W2936187034 cites W2774965031 @default.
- W2936187034 cites W2780574896 @default.
- W2936187034 cites W2807345440 @default.
- W2936187034 doi "https://doi.org/10.1016/j.polymdegradstab.2019.04.008" @default.
- W2936187034 hasPublicationYear "2019" @default.
- W2936187034 type Work @default.
- W2936187034 sameAs 2936187034 @default.
- W2936187034 citedByCount "12" @default.
- W2936187034 countsByYear W29361870342020 @default.
- W2936187034 countsByYear W29361870342021 @default.
- W2936187034 countsByYear W29361870342022 @default.
- W2936187034 countsByYear W29361870342023 @default.
- W2936187034 crossrefType "journal-article" @default.
- W2936187034 hasAuthorship W2936187034A5002415075 @default.
- W2936187034 hasAuthorship W2936187034A5016206959 @default.
- W2936187034 hasAuthorship W2936187034A5019014198 @default.
- W2936187034 hasAuthorship W2936187034A5029504527 @default.
- W2936187034 hasAuthorship W2936187034A5040199434 @default.
- W2936187034 hasAuthorship W2936187034A5046311080 @default.
- W2936187034 hasAuthorship W2936187034A5057107318 @default.
- W2936187034 hasAuthorship W2936187034A5062754890 @default.
- W2936187034 hasAuthorship W2936187034A5068039406 @default.
- W2936187034 hasAuthorship W2936187034A5075702553 @default.
- W2936187034 hasConcept C10138342 @default.
- W2936187034 hasConcept C108586683 @default.
- W2936187034 hasConcept C12554922 @default.
- W2936187034 hasConcept C127413603 @default.
- W2936187034 hasConcept C136229726 @default.
- W2936187034 hasConcept C162324750 @default.
- W2936187034 hasConcept C178790620 @default.
- W2936187034 hasConcept C185592680 @default.
- W2936187034 hasConcept C188027245 @default.
- W2936187034 hasConcept C192562407 @default.
- W2936187034 hasConcept C193855658 @default.
- W2936187034 hasConcept C198826908 @default.
- W2936187034 hasConcept C2777230088 @default.
- W2936187034 hasConcept C2777516009 @default.
- W2936187034 hasConcept C42360764 @default.
- W2936187034 hasConcept C49892992 @default.
- W2936187034 hasConcept C54355233 @default.
- W2936187034 hasConcept C54400483 @default.
- W2936187034 hasConcept C71924100 @default.
- W2936187034 hasConcept C81885089 @default.
- W2936187034 hasConcept C86803240 @default.
- W2936187034 hasConcept C95444343 @default.
- W2936187034 hasConceptScore W2936187034C10138342 @default.
- W2936187034 hasConceptScore W2936187034C108586683 @default.
- W2936187034 hasConceptScore W2936187034C12554922 @default.
- W2936187034 hasConceptScore W2936187034C127413603 @default.
- W2936187034 hasConceptScore W2936187034C136229726 @default.
- W2936187034 hasConceptScore W2936187034C162324750 @default.
- W2936187034 hasConceptScore W2936187034C178790620 @default.