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- W2936229087 abstract "Psoriasis has major negative effects on quality-of-life (QoL) and can appear differently in different skin types and racial/ethnic groups. Little is known about the QoL effects of psoriasis by race/ethnicity. We aimed to evaluate skin-related QoL by race/ethnicity among individuals in North America. We performed a cross-sectional study of baseline data for North American adult participants in the Psoriasis Longitudinal Assessment and Registry (PSOLAR; N=10,107), an international prospective registry of patients with psoriasis who are receiving or are candidates for systemic treatment. Mean age was 48.7 (SD 13.9) and 45.9% were female. We used multivariable logistic regression to assess the association between race/ethnicity (white [reference], black, Asian, Hispanic, other) and Dermatology Life Quality Index score dichotomized as small to extremely large effect (2-30) versus no effect (0-1) on QoL, adjusting for demographics, comorbidity, and psoriasis severity and treatment. Blacks (odds ratio 1.74, 95% CI 1.29-2.34), Asians (1.52, 1.14-2.03), and Hispanics (1.42, 1.12-1.79) were each more likely than whites to report at least a small effect of psoriasis on their QoL, independent of psoriasis severity and other characteristics. In light of prior clinical trial data supporting racial/ethnic differences in QoL among psoriasis patients and other data suggesting racial disparities in biologic treatment and healthcare use for psoriasis, our findings highlight a greater and potentially undertreated QoL burden of psoriasis among minorities in North America." @default.
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- W2936229087 date "2019-05-01" @default.
- W2936229087 modified "2023-10-12" @default.
- W2936229087 title "857 Psoriasis-related quality-of-life differs by race/ethnicity" @default.
- W2936229087 doi "https://doi.org/10.1016/j.jid.2019.03.933" @default.
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