FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2936575940> ?p ?o ?g. }

• W2936575940 abstract "C1q, as a LAIR-1 ligand, maintains monocytes quiescence and possess immunosuppressive properties. To understand the roles and molecular mechanisms, C1q mediated inflammation cytokines and several pivotal proteins in THP-1 cells after H. pylori infection were detected. The results showed that the expression of IL-8, IL-10, LAIR-1, phosphorylated/total JNK, phosphorylated/total p38-MAPK, phosphorylated/total AKT and phosphorylated/total NF-κB were up-regulated significantly in THP-1 cells after H. pylori infection. There was significant upregulation in IL-10 concentration, phosphorylated/total p38-MAPK and phosphorylated/total AKT, and downregulation in phosphorylated/total JNK in non-H. pylori infected THP-1 cells pretreated with C1q. C1q was also able to increase IL-8 and IL-10 production, and reduce LAIR-1 and phosphorylated/total p38-MAPK expression in pretreatment-C1q THP-1 cells after H. pylori infection. These results together indicated that H. pylori might induce IL-8 and IL-10 production through JNK, p38-MAPK, PI3K/AKT and NF-κB signaling pathway. C1q manipulate LAIR-1 to regulation IL-8 and IL-10 secretion in THP-1 cells after H. pylori infection through the p38-MAPK signaling pathway. This information is helpful to further understand the role and mechanisms of C1q on inflammation cytokines secretion in monocytes after H. pylori infection." @default.
• W2936575940 created "2019-04-25" @default.
• W2936575940 creator A5000003233 @default.
• W2936575940 creator A5015437792 @default.
• W2936575940 creator A5021281009 @default.
• W2936575940 creator A5021609912 @default.
• W2936575940 creator A5028503562 @default.
• W2936575940 creator A5042973046 @default.
• W2936575940 creator A5066057809 @default.
• W2936575940 creator A5068369275 @default.
• W2936575940 creator A5076181858 @default.
• W2936575940 creator A5085066668 @default.
• W2936575940 date "2019-06-01" @default.
• W2936575940 modified "2023-10-17" @default.
• W2936575940 title "The regulatory role of C1q on Helicobacter pylori-induced inflammatory cytokines secretion in THP-1 cells" @default.
• W2936575940 cites W1837722486 @default.
• W2936575940 cites W2007422238 @default.
• W2936575940 cites W2088908338 @default.
• W2936575940 cites W2093891415 @default.
• W2936575940 cites W2097902302 @default.
• W2936575940 cites W2119173974 @default.
• W2936575940 cites W2153091201 @default.
• W2936575940 cites W2156013098 @default.
• W2936575940 cites W2162509998 @default.
• W2936575940 cites W2162645937 @default.
• W2936575940 cites W2163371670 @default.
• W2936575940 cites W2173264624 @default.
• W2936575940 cites W2188394931 @default.
• W2936575940 cites W2405665461 @default.
• W2936575940 cites W2521614430 @default.
• W2936575940 cites W2525019996 @default.
• W2936575940 cites W2608178048 @default.
• W2936575940 cites W2626075830 @default.
• W2936575940 cites W2774429545 @default.
• W2936575940 cites W2791103406 @default.
• W2936575940 cites W959290310 @default.
• W2936575940 doi "https://doi.org/10.1016/j.micpath.2019.04.017" @default.
• W2936575940 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30986450" @default.
• W2936575940 hasPublicationYear "2019" @default.
• W2936575940 type Work @default.
• W2936575940 sameAs 2936575940 @default.
• W2936575940 citedByCount "2" @default.
• W2936575940 countsByYear W29365759402020 @default.
• W2936575940 countsByYear W29365759402021 @default.
• W2936575940 crossrefType "journal-article" @default.
• W2936575940 hasAuthorship W2936575940A5000003233 @default.
• W2936575940 hasAuthorship W2936575940A5015437792 @default.
• W2936575940 hasAuthorship W2936575940A5021281009 @default.
• W2936575940 hasAuthorship W2936575940A5021609912 @default.
• W2936575940 hasAuthorship W2936575940A5028503562 @default.
• W2936575940 hasAuthorship W2936575940A5042973046 @default.
• W2936575940 hasAuthorship W2936575940A5066057809 @default.
• W2936575940 hasAuthorship W2936575940A5068369275 @default.
• W2936575940 hasAuthorship W2936575940A5076181858 @default.
• W2936575940 hasAuthorship W2936575940A5085066668 @default.
• W2936575940 hasConcept C104317684 @default.
• W2936575940 hasConcept C11960822 @default.
• W2936575940 hasConcept C127561419 @default.
• W2936575940 hasConcept C164027704 @default.
• W2936575940 hasConcept C187316574 @default.
• W2936575940 hasConcept C203014093 @default.
• W2936575940 hasConcept C204258353 @default.
• W2936575940 hasConcept C2776914184 @default.
• W2936575940 hasConcept C2778690821 @default.
• W2936575940 hasConcept C49039625 @default.
• W2936575940 hasConcept C51551487 @default.
• W2936575940 hasConcept C54355233 @default.
• W2936575940 hasConcept C55493867 @default.
• W2936575940 hasConcept C57074206 @default.
• W2936575940 hasConcept C62478195 @default.
• W2936575940 hasConcept C75217442 @default.
• W2936575940 hasConcept C81885089 @default.
• W2936575940 hasConcept C86554907 @default.
• W2936575940 hasConcept C86803240 @default.
• W2936575940 hasConcept C95444343 @default.
• W2936575940 hasConceptScore W2936575940C104317684 @default.
• W2936575940 hasConceptScore W2936575940C11960822 @default.
• W2936575940 hasConceptScore W2936575940C127561419 @default.
• W2936575940 hasConceptScore W2936575940C164027704 @default.
• W2936575940 hasConceptScore W2936575940C187316574 @default.
• W2936575940 hasConceptScore W2936575940C203014093 @default.
• W2936575940 hasConceptScore W2936575940C204258353 @default.
• W2936575940 hasConceptScore W2936575940C2776914184 @default.
• W2936575940 hasConceptScore W2936575940C2778690821 @default.
• W2936575940 hasConceptScore W2936575940C49039625 @default.
• W2936575940 hasConceptScore W2936575940C51551487 @default.
• W2936575940 hasConceptScore W2936575940C54355233 @default.
• W2936575940 hasConceptScore W2936575940C55493867 @default.
• W2936575940 hasConceptScore W2936575940C57074206 @default.
• W2936575940 hasConceptScore W2936575940C62478195 @default.
• W2936575940 hasConceptScore W2936575940C75217442 @default.
• W2936575940 hasConceptScore W2936575940C81885089 @default.
• W2936575940 hasConceptScore W2936575940C86554907 @default.
• W2936575940 hasConceptScore W2936575940C86803240 @default.
• W2936575940 hasConceptScore W2936575940C95444343 @default.
• W2936575940 hasFunder F4320321001 @default.
• W2936575940 hasFunder F4320324321 @default.
• W2936575940 hasLocation W29365759401 @default.
• W2936575940 hasLocation W29365759402 @default.
• W2936575940 hasOpenAccess W2936575940 @default.

• next