FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2936620676> ?p ?o ?g. }

• W2936620676 endingPage "37" @default.
• W2936620676 startingPage "33" @default.
• W2936620676 abstract "Systemic sclerosis (SSc) is a complicated multisystem disease which is characterized by the highest standardized mortality ratio among all systemic rheumatic diseases with no approved therapies so far. From a pathogenetic point of view it is generally considered that autoimmunity, vasculopathy and fibrosis are the main pathophysiologic processes. In this opinion article/minireview we will discuss current and future options for SSc-related fibrotic manifestations (skin thickening and lung fibrosis). Based on the results of SLS II the best treatment option for skin involvement in SSc is mycophenolate mofetil (MMF). Methotrexate (MTX) is another option which is safe and of low cost but evidence supporting its use is weak. The standard of care for SSc-ILD nowadays is MMF. Patients not responding to MMF could be treated with rituximab (RTX) or cyclophosphamide (CYC) (tocilizumab [TCZ] could be an option as well but only for patients with increased inflammatory markers). Hematopoietic stem cell transplantation (HSCT) could be considered in patients with severe/life-threatening disease who have failed conventional treatment. The most promising therapeutic approach currently been evaluated in phase 3 trials is probably the combination of MMF plus pirfenidone." @default.
• W2936620676 created "2019-04-25" @default.
• W2936620676 creator A5010814285 @default.
• W2936620676 creator A5039944418 @default.
• W2936620676 date "2019-03-01" @default.
• W2936620676 modified "2023-09-30" @default.
• W2936620676 title "Treatment of systemic sclerosis associated fibrotic manifestations: Current options and future directions" @default.
• W2936620676 cites W1519230909 @default.
• W2936620676 cites W2041443103 @default.
• W2936620676 cites W2051747444 @default.
• W2936620676 cites W2056202684 @default.
• W2936620676 cites W2065142023 @default.
• W2936620676 cites W2067475334 @default.
• W2936620676 cites W2080136584 @default.
• W2936620676 cites W2081083759 @default.
• W2936620676 cites W2089781422 @default.
• W2936620676 cites W2095975942 @default.
• W2936620676 cites W2101971767 @default.
• W2936620676 cites W2124445299 @default.
• W2936620676 cites W2131014787 @default.
• W2936620676 cites W2138871107 @default.
• W2936620676 cites W2147543851 @default.
• W2936620676 cites W2149183272 @default.
• W2936620676 cites W2154190410 @default.
• W2936620676 cites W2155049325 @default.
• W2936620676 cites W2156105259 @default.
• W2936620676 cites W2163803019 @default.
• W2936620676 cites W2165096626 @default.
• W2936620676 cites W2165992621 @default.
• W2936620676 cites W2166225174 @default.
• W2936620676 cites W2347093301 @default.
• W2936620676 cites W2498506084 @default.
• W2936620676 cites W2531669554 @default.
• W2936620676 cites W2618103221 @default.
• W2936620676 cites W2782208928 @default.
• W2936620676 cites W2806476436 @default.
• W2936620676 cites W4233799263 @default.
• W2936620676 cites W981460048 @default.
• W2936620676 doi "https://doi.org/10.31138/mjr.30.1.33" @default.
• W2936620676 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7045920" @default.
• W2936620676 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32185340" @default.
• W2936620676 hasPublicationYear "2019" @default.
• W2936620676 type Work @default.
• W2936620676 sameAs 2936620676 @default.
• W2936620676 citedByCount "14" @default.
• W2936620676 countsByYear W29366206762019 @default.
• W2936620676 countsByYear W29366206762020 @default.
• W2936620676 countsByYear W29366206762021 @default.
• W2936620676 countsByYear W29366206762022 @default.
• W2936620676 countsByYear W29366206762023 @default.
• W2936620676 crossrefType "journal-article" @default.
• W2936620676 hasAuthorship W2936620676A5010814285 @default.
• W2936620676 hasAuthorship W2936620676A5039944418 @default.
• W2936620676 hasBestOaLocation W29366206761 @default.
• W2936620676 hasConcept C126322002 @default.
• W2936620676 hasConcept C16005928 @default.
• W2936620676 hasConcept C180032290 @default.
• W2936620676 hasConcept C203014093 @default.
• W2936620676 hasConcept C2776694085 @default.
• W2936620676 hasConcept C2776755627 @default.
• W2936620676 hasConcept C2776760755 @default.
• W2936620676 hasConcept C2777178219 @default.
• W2936620676 hasConcept C2777575956 @default.
• W2936620676 hasConcept C2777714996 @default.
• W2936620676 hasConcept C2778341716 @default.
• W2936620676 hasConcept C2779134260 @default.
• W2936620676 hasConcept C2779338263 @default.
• W2936620676 hasConcept C2779832356 @default.
• W2936620676 hasConcept C2779967694 @default.
• W2936620676 hasConcept C2780559512 @default.
• W2936620676 hasConcept C2780653079 @default.
• W2936620676 hasConcept C2781059491 @default.
• W2936620676 hasConcept C71924100 @default.
• W2936620676 hasConceptScore W2936620676C126322002 @default.
• W2936620676 hasConceptScore W2936620676C16005928 @default.
• W2936620676 hasConceptScore W2936620676C180032290 @default.
• W2936620676 hasConceptScore W2936620676C203014093 @default.
• W2936620676 hasConceptScore W2936620676C2776694085 @default.
• W2936620676 hasConceptScore W2936620676C2776755627 @default.
• W2936620676 hasConceptScore W2936620676C2776760755 @default.
• W2936620676 hasConceptScore W2936620676C2777178219 @default.
• W2936620676 hasConceptScore W2936620676C2777575956 @default.
• W2936620676 hasConceptScore W2936620676C2777714996 @default.
• W2936620676 hasConceptScore W2936620676C2778341716 @default.
• W2936620676 hasConceptScore W2936620676C2779134260 @default.
• W2936620676 hasConceptScore W2936620676C2779338263 @default.
• W2936620676 hasConceptScore W2936620676C2779832356 @default.
• W2936620676 hasConceptScore W2936620676C2779967694 @default.
• W2936620676 hasConceptScore W2936620676C2780559512 @default.
• W2936620676 hasConceptScore W2936620676C2780653079 @default.
• W2936620676 hasConceptScore W2936620676C2781059491 @default.
• W2936620676 hasConceptScore W2936620676C71924100 @default.
• W2936620676 hasIssue "1" @default.
• W2936620676 hasLocation W29366206761 @default.
• W2936620676 hasLocation W29366206762 @default.
• W2936620676 hasLocation W29366206763 @default.
• W2936620676 hasLocation W29366206764 @default.
• W2936620676 hasLocation W29366206765 @default.

• next