FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2936626134> ?p ?o ?g. }

• W2936626134 endingPage "1144" @default.
• W2936626134 startingPage "1135" @default.
• W2936626134 abstract "ObjectiveTo study the influence of human papillomavirus (HPV) virions present in different sperm fractions of male partners of women undergoing IUI on fertility outcome.DesignProspective noninterventional multicenter study.SettingInpatient hospital fertility centers.Patient(s)Seven hundred thirty-two infertile couples undergoing 1,753 IUI cycles with capacitated sperm.Intervention(s)None.Main Outcome Measure(s)Biochemical and clinical pregnancy rate in IUI cycles with HPV-positive or HPV-negative semen.Result(s)Five hundred seventy-three infertile couples undergoing 1,362 IUI cycles were enrolled. Work-up of the 1,362 sperm samples that were used for IUI generated 3,444 separate sperm fractions. Each of the sperm fractions was tested with quantitative polymerase chain reaction for 18 different HPV types (6, 11, 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67, and 68). HPV prevalence in sperm was 12.5%/IUI cycle. When infectious HPV virions were detected in sperm, a significant decrease in clinical pregnancies was observed when compared with HPV-negative cycles (2.9% vs. 11.1 %/cycle). Above a ratio of 0.66 HPV virions/spermatozoon no pregnancies occurred (sensitivity 100%, specificity 32.5%).Conclusion(s)Women inseminated with HPV-positive sperm had 4 times fewer clinical pregnancies compared with women who had HPV-negative partners. Detection of HPV virions in sperm is associated with a negative IUI outcome and should be part of routine examination and counseling of infertile couples.European Clinical Trials Database Number2017-004791–56. To study the influence of human papillomavirus (HPV) virions present in different sperm fractions of male partners of women undergoing IUI on fertility outcome. Prospective noninterventional multicenter study. Inpatient hospital fertility centers. Seven hundred thirty-two infertile couples undergoing 1,753 IUI cycles with capacitated sperm. None. Biochemical and clinical pregnancy rate in IUI cycles with HPV-positive or HPV-negative semen. Five hundred seventy-three infertile couples undergoing 1,362 IUI cycles were enrolled. Work-up of the 1,362 sperm samples that were used for IUI generated 3,444 separate sperm fractions. Each of the sperm fractions was tested with quantitative polymerase chain reaction for 18 different HPV types (6, 11, 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67, and 68). HPV prevalence in sperm was 12.5%/IUI cycle. When infectious HPV virions were detected in sperm, a significant decrease in clinical pregnancies was observed when compared with HPV-negative cycles (2.9% vs. 11.1 %/cycle). Above a ratio of 0.66 HPV virions/spermatozoon no pregnancies occurred (sensitivity 100%, specificity 32.5%). Women inseminated with HPV-positive sperm had 4 times fewer clinical pregnancies compared with women who had HPV-negative partners. Detection of HPV virions in sperm is associated with a negative IUI outcome and should be part of routine examination and counseling of infertile couples." @default.
• W2936626134 created "2019-04-25" @default.
• W2936626134 creator A5016161787 @default.
• W2936626134 creator A5039645858 @default.
• W2936626134 creator A5048817019 @default.
• W2936626134 creator A5052541582 @default.
• W2936626134 creator A5063493723 @default.
• W2936626134 creator A5066838577 @default.
• W2936626134 creator A5067514986 @default.
• W2936626134 creator A5071665734 @default.
• W2936626134 date "2019-06-01" @default.
• W2936626134 modified "2023-10-18" @default.
• W2936626134 title "Infectious human papillomavirus virions in semen reduce clinical pregnancy rates in women undergoing intrauterine insemination" @default.
• W2936626134 cites W1490597472 @default.
• W2936626134 cites W1538683452 @default.
• W2936626134 cites W1564470595 @default.
• W2936626134 cites W1577573172 @default.
• W2936626134 cites W1922130321 @default.
• W2936626134 cites W1937133798 @default.
• W2936626134 cites W1964088434 @default.
• W2936626134 cites W1970307151 @default.
• W2936626134 cites W1971750179 @default.
• W2936626134 cites W1972341971 @default.
• W2936626134 cites W1994275570 @default.
• W2936626134 cites W2001046337 @default.
• W2936626134 cites W2013755105 @default.
• W2936626134 cites W2014523922 @default.
• W2936626134 cites W2018760046 @default.
• W2936626134 cites W2024067295 @default.
• W2936626134 cites W2027172110 @default.
• W2936626134 cites W2031370247 @default.
• W2936626134 cites W2034242326 @default.
• W2936626134 cites W2039353729 @default.
• W2936626134 cites W2054018101 @default.
• W2936626134 cites W2067352335 @default.
• W2936626134 cites W2075692523 @default.
• W2936626134 cites W2084494076 @default.
• W2936626134 cites W2090830060 @default.
• W2936626134 cites W2101196984 @default.
• W2936626134 cites W2123597793 @default.
• W2936626134 cites W2128650021 @default.
• W2936626134 cites W2132639608 @default.
• W2936626134 cites W2132776016 @default.
• W2936626134 cites W2159902645 @default.
• W2936626134 cites W2160907222 @default.
• W2936626134 cites W2168181991 @default.
• W2936626134 cites W2285502977 @default.
• W2936626134 cites W2412361450 @default.
• W2936626134 cites W2472375246 @default.
• W2936626134 cites W2590975248 @default.
• W2936626134 cites W2598769156 @default.
• W2936626134 cites W2741632770 @default.
• W2936626134 cites W2783621719 @default.
• W2936626134 cites W2795586791 @default.
• W2936626134 cites W2891455487 @default.
• W2936626134 doi "https://doi.org/10.1016/j.fertnstert.2019.02.002" @default.
• W2936626134 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31005311" @default.
• W2936626134 hasPublicationYear "2019" @default.
• W2936626134 type Work @default.
• W2936626134 sameAs 2936626134 @default.
• W2936626134 citedByCount "37" @default.
• W2936626134 countsByYear W29366261342018 @default.
• W2936626134 countsByYear W29366261342019 @default.
• W2936626134 countsByYear W29366261342020 @default.
• W2936626134 countsByYear W29366261342021 @default.
• W2936626134 countsByYear W29366261342022 @default.
• W2936626134 countsByYear W29366261342023 @default.
• W2936626134 crossrefType "journal-article" @default.
• W2936626134 hasAuthorship W2936626134A5016161787 @default.
• W2936626134 hasAuthorship W2936626134A5039645858 @default.
• W2936626134 hasAuthorship W2936626134A5048817019 @default.
• W2936626134 hasAuthorship W2936626134A5052541582 @default.
• W2936626134 hasAuthorship W2936626134A5063493723 @default.
• W2936626134 hasAuthorship W2936626134A5066838577 @default.
• W2936626134 hasAuthorship W2936626134A5067514986 @default.
• W2936626134 hasAuthorship W2936626134A5071665734 @default.
• W2936626134 hasBestOaLocation W29366261341 @default.
• W2936626134 hasConcept C126322002 @default.
• W2936626134 hasConcept C127315564 @default.
• W2936626134 hasConcept C131872663 @default.
• W2936626134 hasConcept C16685009 @default.
• W2936626134 hasConcept C2776537878 @default.
• W2936626134 hasConcept C2777005246 @default.
• W2936626134 hasConcept C2777589648 @default.
• W2936626134 hasConcept C2777688143 @default.
• W2936626134 hasConcept C2778093475 @default.
• W2936626134 hasConcept C2778610407 @default.
• W2936626134 hasConcept C2779234561 @default.
• W2936626134 hasConcept C2781087480 @default.
• W2936626134 hasConcept C2908647359 @default.
• W2936626134 hasConcept C29456083 @default.
• W2936626134 hasConcept C2994532551 @default.
• W2936626134 hasConcept C518429986 @default.
• W2936626134 hasConcept C54355233 @default.
• W2936626134 hasConcept C71924100 @default.
• W2936626134 hasConcept C86803240 @default.
• W2936626134 hasConcept C99454951 @default.
• W2936626134 hasConceptScore W2936626134C126322002 @default.

• next