FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2936732197> ?p ?o ?g. }

• W2936732197 abstract "Porcine reproductive and respiratory syndrome virus (PRRSV) is known to be clinically responsible for reproductive failure in sows and post-weaning respiratory disease in growing piglets. During the last years, highly pathogenic PRRSV isolates have been discovered. In Italy, a PRRSV-1 subtype 1 strain (namely PR40/2014) characterized by high pathogenicity was isolated and experimental infection was characterized in terms of virological/clinical features and immune modulation (Canelli et al., 2017; Ferrari et al., 2018). The present study was performed in 4-week-old pigs experimentally infected with the highly pathogenic PRRSV1_PR40/2014 (HP-PR40) or with the conventional PRRSV1_PR11/2014 (PR11). The aim was to evaluate the interrelation between plasmatic hormones and cytokines in infected pigs compared to uninfected controls in order to address potential effects on the course of an experimental infection. The time-related changes of growth hormone (GH), insulin-like growth factor-1 (IGF-1), adiponectin, interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) levels appear to be modulated by the infection depending on the PRRSV isolate (HP-PR40 vs. PR11). In particular, in HP-PR40 infected animals, the association between high GH levels and viremia may testify the need to block the anabolic action of GH in order to shift available energy towards the immune response. This need appeared to be delayed in PR11 animals, given the lower pathogenicity of the isolate. Adiponectin, IL-6 and TNF-α course supports the hypothesis of GH resistance mechanisms to guarantee homeostasis in HP-PR40 animals and underlines the key role of energy availability in events leading to an effective response to the virus." @default.
• W2936732197 created "2019-04-25" @default.
• W2936732197 creator A5001384115 @default.
• W2936732197 creator A5007303654 @default.
• W2936732197 creator A5008918471 @default.
• W2936732197 creator A5026730063 @default.
• W2936732197 creator A5046052187 @default.
• W2936732197 creator A5061014162 @default.
• W2936732197 creator A5085823821 @default.
• W2936732197 date "2019-06-01" @default.
• W2936732197 modified "2023-09-24" @default.
• W2936732197 title "Modulation of the somatotropic axis, adiponectin and cytokine secretion during highly pathogenic porcine reproductive and respiratory syndrome virus type 1 (HP-PRRSV-1) infection" @default.
• W2936732197 cites W1486014609 @default.
• W2936732197 cites W1501655398 @default.
• W2936732197 cites W1983467035 @default.
• W2936732197 cites W1984646945 @default.
• W2936732197 cites W2005505978 @default.
• W2936732197 cites W2014570432 @default.
• W2936732197 cites W2019536816 @default.
• W2936732197 cites W2019542752 @default.
• W2936732197 cites W2030014151 @default.
• W2936732197 cites W2036303156 @default.
• W2936732197 cites W2053208961 @default.
• W2936732197 cites W2056788640 @default.
• W2936732197 cites W2060782260 @default.
• W2936732197 cites W2061912250 @default.
• W2936732197 cites W2065697164 @default.
• W2936732197 cites W2065786953 @default.
• W2936732197 cites W2077650203 @default.
• W2936732197 cites W2081258545 @default.
• W2936732197 cites W2082068419 @default.
• W2936732197 cites W2097144006 @default.
• W2936732197 cites W2100478793 @default.
• W2936732197 cites W2103692755 @default.
• W2936732197 cites W2130145755 @default.
• W2936732197 cites W2133102204 @default.
• W2936732197 cites W2135579409 @default.
• W2936732197 cites W2137219871 @default.
• W2936732197 cites W2146955829 @default.
• W2936732197 cites W2345473206 @default.
• W2936732197 cites W2397468189 @default.
• W2936732197 cites W2407348647 @default.
• W2936732197 cites W2417184155 @default.
• W2936732197 cites W2470404765 @default.
• W2936732197 cites W2500162161 @default.
• W2936732197 cites W2533912062 @default.
• W2936732197 cites W2605606775 @default.
• W2936732197 cites W2613920830 @default.
• W2936732197 cites W2755120623 @default.
• W2936732197 cites W2777753808 @default.
• W2936732197 cites W2790158719 @default.
• W2936732197 cites W2896584144 @default.
• W2936732197 cites W970789458 @default.
• W2936732197 doi "https://doi.org/10.1016/j.rvsc.2019.04.007" @default.
• W2936732197 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31003008" @default.
• W2936732197 hasPublicationYear "2019" @default.
• W2936732197 type Work @default.
• W2936732197 sameAs 2936732197 @default.
• W2936732197 citedByCount "3" @default.
• W2936732197 countsByYear W29367321972020 @default.
• W2936732197 countsByYear W29367321972022 @default.
• W2936732197 crossrefType "journal-article" @default.
• W2936732197 hasAuthorship W2936732197A5001384115 @default.
• W2936732197 hasAuthorship W2936732197A5007303654 @default.
• W2936732197 hasAuthorship W2936732197A5008918471 @default.
• W2936732197 hasAuthorship W2936732197A5026730063 @default.
• W2936732197 hasAuthorship W2936732197A5046052187 @default.
• W2936732197 hasAuthorship W2936732197A5061014162 @default.
• W2936732197 hasAuthorship W2936732197A5085823821 @default.
• W2936732197 hasConcept C126322002 @default.
• W2936732197 hasConcept C134018914 @default.
• W2936732197 hasConcept C159047783 @default.
• W2936732197 hasConcept C17991360 @default.
• W2936732197 hasConcept C203014093 @default.
• W2936732197 hasConcept C2522874641 @default.
• W2936732197 hasConcept C2776185481 @default.
• W2936732197 hasConcept C2778690821 @default.
• W2936732197 hasConcept C2779819720 @default.
• W2936732197 hasConcept C71924100 @default.
• W2936732197 hasConcept C86803240 @default.
• W2936732197 hasConcept C8891405 @default.
• W2936732197 hasConceptScore W2936732197C126322002 @default.
• W2936732197 hasConceptScore W2936732197C134018914 @default.
• W2936732197 hasConceptScore W2936732197C159047783 @default.
• W2936732197 hasConceptScore W2936732197C17991360 @default.
• W2936732197 hasConceptScore W2936732197C203014093 @default.
• W2936732197 hasConceptScore W2936732197C2522874641 @default.
• W2936732197 hasConceptScore W2936732197C2776185481 @default.
• W2936732197 hasConceptScore W2936732197C2778690821 @default.
• W2936732197 hasConceptScore W2936732197C2779819720 @default.
• W2936732197 hasConceptScore W2936732197C71924100 @default.
• W2936732197 hasConceptScore W2936732197C86803240 @default.
• W2936732197 hasConceptScore W2936732197C8891405 @default.
• W2936732197 hasLocation W29367321971 @default.
• W2936732197 hasLocation W29367321972 @default.
• W2936732197 hasOpenAccess W2936732197 @default.
• W2936732197 hasPrimaryLocation W29367321971 @default.
• W2936732197 hasRelatedWork W1487857142 @default.
• W2936732197 hasRelatedWork W1966663539 @default.
• W2936732197 hasRelatedWork W1990717759 @default.

• next