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- W2937151910 abstract "While the pathogenesis of Parkinson’s disease is not fully understood, there is increasing evidence that inflammatory responses in the brain are implicated in both disease initiation and progression. The inflammatory process in Parkinson’s disease is, however, not limited to the brain but also involves the gastrointestinal tract. High amounts of cytokines and inflammatory markers are found in the colon of Parkinson’s disease patients and there is now strong epidemiological and genetical evidence linking Parkinson’s disease to inflammatory bowel diseases. Recent findings obtained in both experimental inflammatory bowel diseases and Parkinson’s disease further support a bidirectional link between gastrointestinal inflammation and brain neurodegeneration. Altogether, these observations suggest a role for gastrointestinal inflammation in the initiation and progression of Parkinson’s disease." @default.
- W2937151910 created "2019-04-25" @default.
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- W2937151910 date "2019-04-12" @default.
- W2937151910 modified "2023-10-17" @default.
- W2937151910 title "Is Parkinson’s disease a chronic low-grade inflammatory bowel disease?" @default.
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- W2937151910 doi "https://doi.org/10.1007/s00415-019-09321-0" @default.
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