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- W2937263313 abstract "A series of indane-based phosphine-oxazoline ligands with a spirocarbon stereogenic center were examined for palladium-catalyzed asymmetric allylic alkylation of indoles. Under optimized conditions, high yields (up to 98%) and enantioselectivities (up to 98% ee) were obtained with a broad scope of indole derivatives. The ligand was determined to be the most efficient P,N-ligand for this reaction. Moreover, the ligand was also efficient for Pd-catalyzed asymmetric allylic etherification with hard aliphatic alcohols as nucleophiles." @default.
- W2937263313 created "2019-04-25" @default.
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- W2937263313 date "2019-04-21" @default.
- W2937263313 modified "2023-10-16" @default.
- W2937263313 title "Spiro Indane-Based Phosphine-Oxazolines as Highly Efficient P,N Ligands for Enantioselective Pd-Catalyzed Allylic Alkylation of Indoles and Allylic Etherification" @default.
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- W2937263313 doi "https://doi.org/10.3390/molecules24081575" @default.
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