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• W2937346329 abstract "Abstract Motivation Bioactive peptides have gained great attention in the academy and pharmaceutical industry since they play an important role in human health. However, the increasing number of bioactive peptide databases is causing the problem of data redundancy and duplicated efforts. Even worse is the fact that the available data is non-standardized and often dirty with data entry errors. Therefore, there is a need for a unified view that enables a more comprehensive analysis of the information on this topic residing at different sites. Results After collecting web pages from a large variety of bioactive peptide databases, we organized the web content into an integrated graph database (starPepDB) that holds a total of 71 310 nodes and 348 505 relationships. In this graph structure, there are 45 120 nodes representing peptides, and the rest of the nodes are connected to peptides for describing metadata. Additionally, to facilitate a better understanding of the integrated data, a software tool (starPep toolbox) has been developed for supporting visual network analysis in a user-friendly way; providing several functionalities such as peptide retrieval and filtering, network construction and visualization, interactive exploration and exporting data options. Availability and implementation Both starPepDB and starPep toolbox are freely available at http://mobiosd-hub.com/starpep/. Supplementary information Supplementary data are available at Bioinformatics online." @default.
• W2937346329 created "2019-04-25" @default.
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• W2937346329 date "2019-04-17" @default.
• W2937346329 modified "2023-10-03" @default.
• W2937346329 title "Graph-based data integration from bioactive peptide databases of pharmaceutical interest: toward an organized collection enabling visual network analysis" @default.
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• W2937346329 doi "https://doi.org/10.1093/bioinformatics/btz260" @default.
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