Matches in SemOpenAlex for { <https://semopenalex.org/work/W2937452521> ?p ?o ?g. }
- W2937452521 endingPage "174" @default.
- W2937452521 startingPage "174" @default.
- W2937452521 abstract "Sturgeons also known as living fossils are facing threats to their survival due to overfishing and interference in natural habitats. Sterlet (Acipenser ruthenus) due to its rapid reproductive cycle and small body size can be used as a sterile host for surrogate production for late maturing and large sturgeon species. Dead end protein (dnd1) is essential for migration of Primordial Germ Cells (PGCs), the origin of all germ cells in developing embryos. Knockout or knockdown of dnd1 can be done in order to mismigrate PGCs. Previously we have used MO and UV for the aforementioned purpose, and in our present study we have used CRISPR/Cas9 technology to knockout dnd1. No or a smaller number of PGCs were detected in crispants, and we also observed malformations in some CRISPR/Cas9 injected embryos. Furthermore, we compared three established methods to achieve sterility in sterlet, and we found higher embryo survival and hatching rates in CRISPR/Cas9, UV and MO, respectively." @default.
- W2937452521 created "2019-04-25" @default.
- W2937452521 creator A5014122484 @default.
- W2937452521 creator A5017690299 @default.
- W2937452521 creator A5019327785 @default.
- W2937452521 creator A5025274553 @default.
- W2937452521 creator A5065830106 @default.
- W2937452521 creator A5081326540 @default.
- W2937452521 date "2019-04-17" @default.
- W2937452521 modified "2023-10-14" @default.
- W2937452521 title "Dnd1 Knockout in Sturgeons By CRISPR/Cas9 Generates Germ Cell Free Host for Surrogate Production" @default.
- W2937452521 cites W1112527103 @default.
- W2937452521 cites W1493535861 @default.
- W2937452521 cites W1567081844 @default.
- W2937452521 cites W1838932699 @default.
- W2937452521 cites W1873280552 @default.
- W2937452521 cites W1892455518 @default.
- W2937452521 cites W1907912454 @default.
- W2937452521 cites W1965424196 @default.
- W2937452521 cites W1970549334 @default.
- W2937452521 cites W1983538883 @default.
- W2937452521 cites W1997928390 @default.
- W2937452521 cites W2001845502 @default.
- W2937452521 cites W2004173231 @default.
- W2937452521 cites W2017224987 @default.
- W2937452521 cites W2020128982 @default.
- W2937452521 cites W2022030472 @default.
- W2937452521 cites W2028641896 @default.
- W2937452521 cites W2047784091 @default.
- W2937452521 cites W2051401308 @default.
- W2937452521 cites W2060569777 @default.
- W2937452521 cites W2068983765 @default.
- W2937452521 cites W2074641301 @default.
- W2937452521 cites W2095216685 @default.
- W2937452521 cites W2096101857 @default.
- W2937452521 cites W2096261947 @default.
- W2937452521 cites W2097464871 @default.
- W2937452521 cites W2100158033 @default.
- W2937452521 cites W2104654535 @default.
- W2937452521 cites W2122136549 @default.
- W2937452521 cites W2132102978 @default.
- W2937452521 cites W2152083180 @default.
- W2937452521 cites W2155764320 @default.
- W2937452521 cites W2157334713 @default.
- W2937452521 cites W2159271387 @default.
- W2937452521 cites W2162117475 @default.
- W2937452521 cites W2164695230 @default.
- W2937452521 cites W2227085397 @default.
- W2937452521 cites W2229227489 @default.
- W2937452521 cites W2276479673 @default.
- W2937452521 cites W2293081830 @default.
- W2937452521 cites W2398286517 @default.
- W2937452521 cites W2428582354 @default.
- W2937452521 cites W2530129311 @default.
- W2937452521 cites W2531727263 @default.
- W2937452521 cites W2606387661 @default.
- W2937452521 cites W2621965933 @default.
- W2937452521 cites W2760154987 @default.
- W2937452521 cites W2781575090 @default.
- W2937452521 cites W2787558597 @default.
- W2937452521 cites W2794949547 @default.
- W2937452521 cites W2796432498 @default.
- W2937452521 cites W2796444319 @default.
- W2937452521 cites W2800333696 @default.
- W2937452521 cites W2913968992 @default.
- W2937452521 cites W4239363531 @default.
- W2937452521 doi "https://doi.org/10.3390/ani9040174" @default.
- W2937452521 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6523263" @default.
- W2937452521 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30999629" @default.
- W2937452521 hasPublicationYear "2019" @default.
- W2937452521 type Work @default.
- W2937452521 sameAs 2937452521 @default.
- W2937452521 citedByCount "27" @default.
- W2937452521 countsByYear W29374525212019 @default.
- W2937452521 countsByYear W29374525212020 @default.
- W2937452521 countsByYear W29374525212021 @default.
- W2937452521 countsByYear W29374525212022 @default.
- W2937452521 countsByYear W29374525212023 @default.
- W2937452521 crossrefType "journal-article" @default.
- W2937452521 hasAuthorship W2937452521A5014122484 @default.
- W2937452521 hasAuthorship W2937452521A5017690299 @default.
- W2937452521 hasAuthorship W2937452521A5019327785 @default.
- W2937452521 hasAuthorship W2937452521A5025274553 @default.
- W2937452521 hasAuthorship W2937452521A5065830106 @default.
- W2937452521 hasAuthorship W2937452521A5081326540 @default.
- W2937452521 hasBestOaLocation W29374525211 @default.
- W2937452521 hasConcept C104317684 @default.
- W2937452521 hasConcept C132455925 @default.
- W2937452521 hasConcept C173396325 @default.
- W2937452521 hasConcept C196843134 @default.
- W2937452521 hasConcept C2779122487 @default.
- W2937452521 hasConcept C54355233 @default.
- W2937452521 hasConcept C77957584 @default.
- W2937452521 hasConcept C86803240 @default.
- W2937452521 hasConcept C90856448 @default.
- W2937452521 hasConcept C95444343 @default.
- W2937452521 hasConcept C98108389 @default.
- W2937452521 hasConceptScore W2937452521C104317684 @default.