Matches in SemOpenAlex for { <https://semopenalex.org/work/W2937468165> ?p ?o ?g. }
- W2937468165 abstract "Functional communications between nervous, endocrine and immune systems are well established in both vertebrates and invertebrates. Circulating hemocytes act as fundamental players in this crosstalk, whose functions are conserved during the evolution of the main groups of metazoans. However, the roles of the neuroendocrine-immune (NEI) system in shrimp hemocytes during pathogen infection remain largely unknown. In this study, we sequenced six cDNA libraries prepared with hemocytes from Litopenaeus vannamei which were injected by WSSV (white spot syndrome virus) or PBS for 6 h using Illumina Hiseq 4000 platform. As a result, 3444 differentially expressed genes (DEGs), including 3240 up-regulated genes and 204 down-regulated genes, were identified from hemocytes after WSSV infection. Among these genes, 349 DEGs were correlated with innate immunity and categorized into seven groups based on their predictive function. Interestingly, 18 genes encoded putative neuropeptide precursors were induced significantly by WSSV infection. Furthermore, some genes were mapped to several typical processes in the NEI system, including proteolytic processing of prohormones, amino acid neurotransmitter pathways, biogenic amine biosynthesis and acetylcholine signaling pathway. The data suggested that WSSV infection triggers the activation of NEI in shrimp, which throws a light on the pivotal roles of NEI system mediated by hemocytes in shrimp antiviral immunity." @default.
- W2937468165 created "2019-04-25" @default.
- W2937468165 creator A5018099072 @default.
- W2937468165 creator A5019893417 @default.
- W2937468165 creator A5048943499 @default.
- W2937468165 creator A5054681919 @default.
- W2937468165 date "2019-03-28" @default.
- W2937468165 modified "2023-10-11" @default.
- W2937468165 title "Transcriptome analysis reveals the activation of neuroendocrine-immune system in shrimp hemocytes at the early stage of WSSV infection" @default.
- W2937468165 cites W1584471230 @default.
- W2937468165 cites W174377947 @default.
- W2937468165 cites W1877089504 @default.
- W2937468165 cites W1964142551 @default.
- W2937468165 cites W1964841183 @default.
- W2937468165 cites W1974029263 @default.
- W2937468165 cites W1974991586 @default.
- W2937468165 cites W1975334114 @default.
- W2937468165 cites W1980312793 @default.
- W2937468165 cites W1981261198 @default.
- W2937468165 cites W1982305634 @default.
- W2937468165 cites W1989039610 @default.
- W2937468165 cites W1997898833 @default.
- W2937468165 cites W1997917204 @default.
- W2937468165 cites W1999061814 @default.
- W2937468165 cites W1999870958 @default.
- W2937468165 cites W2003587139 @default.
- W2937468165 cites W2004376232 @default.
- W2937468165 cites W2004811108 @default.
- W2937468165 cites W2010323988 @default.
- W2937468165 cites W2011814478 @default.
- W2937468165 cites W2013734734 @default.
- W2937468165 cites W2027848881 @default.
- W2937468165 cites W2029017855 @default.
- W2937468165 cites W2033617388 @default.
- W2937468165 cites W2036862493 @default.
- W2937468165 cites W2041069637 @default.
- W2937468165 cites W2042177179 @default.
- W2937468165 cites W2047612169 @default.
- W2937468165 cites W2050485762 @default.
- W2937468165 cites W2054683291 @default.
- W2937468165 cites W2054893788 @default.
- W2937468165 cites W2054978122 @default.
- W2937468165 cites W2056035374 @default.
- W2937468165 cites W2059905270 @default.
- W2937468165 cites W2059991997 @default.
- W2937468165 cites W2065891436 @default.
- W2937468165 cites W2066609350 @default.
- W2937468165 cites W2067616225 @default.
- W2937468165 cites W2069001768 @default.
- W2937468165 cites W2070156683 @default.
- W2937468165 cites W2072576888 @default.
- W2937468165 cites W2074979238 @default.
- W2937468165 cites W2079231292 @default.
- W2937468165 cites W2084851667 @default.
- W2937468165 cites W2085832613 @default.
- W2937468165 cites W2094222285 @default.
- W2937468165 cites W2094324857 @default.
- W2937468165 cites W2094906883 @default.
- W2937468165 cites W2096596075 @default.
- W2937468165 cites W2101972919 @default.
- W2937468165 cites W2106238046 @default.
- W2937468165 cites W2107498496 @default.
- W2937468165 cites W2114720901 @default.
- W2937468165 cites W2120640870 @default.
- W2937468165 cites W2123825516 @default.
- W2937468165 cites W2126419817 @default.
- W2937468165 cites W2133579817 @default.
- W2937468165 cites W2136804550 @default.
- W2937468165 cites W2144924711 @default.
- W2937468165 cites W2151889908 @default.
- W2937468165 cites W2158404383 @default.
- W2937468165 cites W2161917727 @default.
- W2937468165 cites W2164154943 @default.
- W2937468165 cites W2168531704 @default.
- W2937468165 cites W2171799151 @default.
- W2937468165 cites W2172377009 @default.
- W2937468165 cites W2187903924 @default.
- W2937468165 cites W2402177553 @default.
- W2937468165 cites W2402708657 @default.
- W2937468165 cites W2527090679 @default.
- W2937468165 cites W2536516812 @default.
- W2937468165 cites W2588526112 @default.
- W2937468165 cites W2776031913 @default.
- W2937468165 cites W2792809997 @default.
- W2937468165 cites W2802093706 @default.
- W2937468165 cites W2950408025 @default.
- W2937468165 cites W4237270607 @default.
- W2937468165 cites W4240896746 @default.
- W2937468165 cites W840778854 @default.
- W2937468165 doi "https://doi.org/10.1186/s12864-019-5614-4" @default.
- W2937468165 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6437892" @default.
- W2937468165 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30922216" @default.
- W2937468165 hasPublicationYear "2019" @default.
- W2937468165 type Work @default.
- W2937468165 sameAs 2937468165 @default.
- W2937468165 citedByCount "26" @default.
- W2937468165 countsByYear W29374681652019 @default.
- W2937468165 countsByYear W29374681652020 @default.
- W2937468165 countsByYear W29374681652021 @default.
- W2937468165 countsByYear W29374681652022 @default.