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• W2937532181 abstract "Previous results based on dietary recall suggest that the ability to adjust eaten quantities to food energy density (ED) may deteriorate around the age of 1 y. However, this hypothesis has not been investigated experimentally. The first aim of the study was to describe changes in the short-term caloric compensation ability of infants around the age of 1 y. We expected a decrease in this ability with age. The second aim was to identify individual factors [e.g., breastfeeding duration, body mass index (BMI) z-score, and change in BMI z-score] related to interindividual variations in caloric compensation ability. We adapted the preload paradigm to calculate a COMPX score. The measure was performed in the laboratory at 11 and 15mo. The parent offered a food preload that was either low or high in ED (LED=33kcal/100g or HED=97.9kcal/100g, respectively), followed by an ad libitum meal after 25 min. The infants were measured and weighed. Information about the infants’ milk-feeding history was collected. We obtained COMPX scores at 11 and 15 mo for 31 infants (12 females). As hypothesized, the caloric compensation ability significantly decreased with age (COMPX11=52%±133%; COMPX15=−14%±151%; P=0.03). The more the COMPX score decreased, the more the BMI z-score between 11 and 15 mo increased (P=0.03) and the higher the BMI z-score was at 2 y (P=0.03). No associations were found between COMPX scores and breastfeeding duration (all P>0.60). Caloric compensation ability decreases between 11 and 15 mo. This decrease is associated with a larger increase in weight status from 11 to 15 mo and a higher weight status at 2 y. This study calls for further research to better understand the early determinants of caloric compensation ability. This trial was registered at www.clinicaltrials.gov as NCT03409042 (https://clinicaltrials.gov/ct2/show/NCT03409042)." @default.
• W2937532181 created "2019-04-25" @default.
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• W2937532181 date "2019-05-01" @default.
• W2937532181 modified "2023-10-16" @default.
• W2937532181 title "Caloric compensation in infants: developmental changes around the age of 1 year and associations with anthropometric measurements up to 2 years" @default.
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• W2937532181 doi "https://doi.org/10.1093/ajcn/nqy357" @default.
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