Matches in SemOpenAlex for { <https://semopenalex.org/work/W2937611907> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2937611907 abstract "Abstract Presepsin, a glycoprotein produced during bacterial phagocytosis, has attracted attention as a sepsis marker for bacterial infections. However, since presepsin is affected by renal function, there is a need to separate the evaluation criteria for diagnosis of healthy subjects from that of patients with renal disorder. In this study, we analyzed the influence of kidney function on presepsin concentrations and recalculated the reference range based on the findings. For this purpose, EDTA-whole blood from 47 healthy subjects and 85 patients with chronic kidney disease was collected and used for presepsin measurement by PATHFAST. Presepsin was found to be significantly correlated with creatinine (r = 0.834), eGFRcreat (r = 0.837), cystatin-C (r = 0.845) and eGFRcys (r = 0.879). Furthermore, in patients with chronic kidney disease at different glomerular filtration rate stages, the presepsin levels showed a significant increasing trend with advancing glomerular filtration rate stage. The reference range, calculated by nonparametric method using a total of 67 cases of healthy volunteers and patients with chronic kidney disease G1, was found to be 59–153 pg/mL, which was notably lower than the standard reference range currently used. Presepsin concentrations were positively correlated with some biomarkers of renal function, indicating that it is necessary to consider the influence of renal function in patients with renal impairment. Further, the recalculated reference range might be more useful for diagnosis and treatment of sepsis than the standard reference currently in use, which likely includes false high values." @default.
- W2937611907 created "2019-04-25" @default.
- W2937611907 creator A5000700201 @default.
- W2937611907 creator A5016939629 @default.
- W2937611907 creator A5018833130 @default.
- W2937611907 creator A5033041040 @default.
- W2937611907 creator A5063192034 @default.
- W2937611907 creator A5081986737 @default.
- W2937611907 date "2019-04-10" @default.
- W2937611907 modified "2023-09-26" @default.
- W2937611907 title "Clinical evaluation of presepsin considering renal function" @default.
- W2937611907 cites W1606470965 @default.
- W2937611907 cites W1918338124 @default.
- W2937611907 cites W2007675575 @default.
- W2937611907 cites W2029157767 @default.
- W2937611907 cites W2044487504 @default.
- W2937611907 cites W2054515061 @default.
- W2937611907 cites W2083897105 @default.
- W2937611907 cites W2121960517 @default.
- W2937611907 cites W2161429816 @default.
- W2937611907 cites W2570771899 @default.
- W2937611907 cites W2752063292 @default.
- W2937611907 cites W3021951158 @default.
- W2937611907 cites W566348055 @default.
- W2937611907 doi "https://doi.org/10.1101/604991" @default.
- W2937611907 hasPublicationYear "2019" @default.
- W2937611907 type Work @default.
- W2937611907 sameAs 2937611907 @default.
- W2937611907 citedByCount "0" @default.
- W2937611907 crossrefType "posted-content" @default.
- W2937611907 hasAuthorship W2937611907A5000700201 @default.
- W2937611907 hasAuthorship W2937611907A5016939629 @default.
- W2937611907 hasAuthorship W2937611907A5018833130 @default.
- W2937611907 hasAuthorship W2937611907A5033041040 @default.
- W2937611907 hasAuthorship W2937611907A5063192034 @default.
- W2937611907 hasAuthorship W2937611907A5081986737 @default.
- W2937611907 hasBestOaLocation W29376119071 @default.
- W2937611907 hasConcept C126322002 @default.
- W2937611907 hasConcept C126894567 @default.
- W2937611907 hasConcept C134018914 @default.
- W2937611907 hasConcept C159641895 @default.
- W2937611907 hasConcept C2778143274 @default.
- W2937611907 hasConcept C2778384902 @default.
- W2937611907 hasConcept C2778653478 @default.
- W2937611907 hasConcept C2779548226 @default.
- W2937611907 hasConcept C2780306776 @default.
- W2937611907 hasConcept C71924100 @default.
- W2937611907 hasConcept C90924648 @default.
- W2937611907 hasConceptScore W2937611907C126322002 @default.
- W2937611907 hasConceptScore W2937611907C126894567 @default.
- W2937611907 hasConceptScore W2937611907C134018914 @default.
- W2937611907 hasConceptScore W2937611907C159641895 @default.
- W2937611907 hasConceptScore W2937611907C2778143274 @default.
- W2937611907 hasConceptScore W2937611907C2778384902 @default.
- W2937611907 hasConceptScore W2937611907C2778653478 @default.
- W2937611907 hasConceptScore W2937611907C2779548226 @default.
- W2937611907 hasConceptScore W2937611907C2780306776 @default.
- W2937611907 hasConceptScore W2937611907C71924100 @default.
- W2937611907 hasConceptScore W2937611907C90924648 @default.
- W2937611907 hasLocation W29376119071 @default.
- W2937611907 hasLocation W29376119072 @default.
- W2937611907 hasOpenAccess W2937611907 @default.
- W2937611907 hasPrimaryLocation W29376119071 @default.
- W2937611907 hasRelatedWork W1971522572 @default.
- W2937611907 hasRelatedWork W1995879404 @default.
- W2937611907 hasRelatedWork W2047597909 @default.
- W2937611907 hasRelatedWork W2104767779 @default.
- W2937611907 hasRelatedWork W2144649651 @default.
- W2937611907 hasRelatedWork W2147235811 @default.
- W2937611907 hasRelatedWork W2157185461 @default.
- W2937611907 hasRelatedWork W2171503067 @default.
- W2937611907 hasRelatedWork W2183150468 @default.
- W2937611907 hasRelatedWork W2231444950 @default.
- W2937611907 hasRelatedWork W2237233272 @default.
- W2937611907 hasRelatedWork W2292665616 @default.
- W2937611907 hasRelatedWork W2348032088 @default.
- W2937611907 hasRelatedWork W2366295384 @default.
- W2937611907 hasRelatedWork W2378139673 @default.
- W2937611907 hasRelatedWork W2399051876 @default.
- W2937611907 hasRelatedWork W2415205929 @default.
- W2937611907 hasRelatedWork W2615825021 @default.
- W2937611907 hasRelatedWork W2783852431 @default.
- W2937611907 hasRelatedWork W3160764172 @default.
- W2937611907 isParatext "false" @default.
- W2937611907 isRetracted "false" @default.
- W2937611907 magId "2937611907" @default.
- W2937611907 workType "article" @default.