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• W2937788462 abstract "ObjectiveSevere asthma is a difficult condition to treat; high-dose corticoids may ultimately represent a risk for patients and are not always enough to relieve them. Some find they in a therapeutic dead-end and have no other perspective than a clinical trial to help them to acquire a better quality of life and no long fearing a life-threatening exacerbation.With such a strong influence in their decision, was it still consent or a coerced choice?MethodsThe study used a qualitative descriptive design consisting of 20 face-to-face interviews of patients with severe uncontrolled asthma who have consent to clinical trials in Marseille, France. Transcribed interviews were analyzed through thematic content analysis then discussed using philosophical tools.ResultsTwo main themes have emerged: (1) the confusion between constraint and influence concerning the disease and the consent itself (2) the important role of the medical staff in the patient consent whom have a full confidence in their judgment. Patients are often confused when they talk about their decision making but when they think through, they feel like they had the choice and they were grateful to be able to participate. They also rely on their doctors to explain the forms instead of reading them, thus risking giving a not so informed consent.ConclusionPatients were performing voluntary actions in a context repressing their freedoms, but not annihilating it. They were not forced by others to integrate the protocol, they were influenced by the disease but they decided freely and voluntarily, so in this situation, influenced choices can be consented. However, relying only on doctors’ intelligences instead of reading consent forms remain an ethical issue because of the potentially biased lightening it implies." @default.
• W2937788462 created "2019-04-25" @default.
• W2937788462 creator A5033027517 @default.
• W2937788462 date "2018-01-01" @default.
• W2937788462 modified "2023-09-28" @default.
• W2937788462 title "Can Influenced Choices be Consented? A Qualitative Study Involving Patients with Severe Uncontrolled Asthma Participating to Clinical Trials" @default.
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