FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2937860281> ?p ?o ?g. }

• W2937860281 endingPage "292" @default.
• W2937860281 startingPage "284" @default.
• W2937860281 abstract "West Nile virus (WNV) is a mosquito-borne zoonotic neurotropic virus capable to cause lethal meningoencephalitis (WNE) in infected hosts such as birds, horses, and humans. Due to their sensitivity, horses serve as sentinel species in areas at risk. We studied a population of Camargue horses living in Southern France in two zones with endemic WNV circulation where WNV outbreaks were recorded in 2000 and 2003–4. Two sets of microsatellite markers located in MHC and Ly49 genomic regions were genotyped as well as multiple SNPs in ten immunity-related candidate gene regions. Associations between genetic polymorphisms and resistance/susceptibility to WNE were tested. While single marker associations were weak, compound two-gene genotypes of SNPs located within the MAVS, NCR2 and IL-10 genes and microsatellites HMS082 and CZM013 were associated with susceptibility to WNE. Combinations of microsatellite markers CZM009, ABGe17402 and ABGe9019 were associated with simple seroconversion without clinical signs of WNE (resistance). In addition, a distribution of polymorphic markers between WNV-IgG seropositive horses and a control group of WNV-IgG seronegative horses was tested. One SNP in the OAS1 gene (NC_009151.3:g.21961328A>G) was significantly associated with the seropositive phenotype (pcorr = 0.023; OR = 40.5 CI (4.28; 383.26); RR = 8.18 CI (1.27; 52.89) in the Camargue breed. In compound genotypes, SNP markers for SLC11A1, MAVS, OAS1, TLR4, ADAM17 and NCR2 genes and ten microsatellites showed non-random distribution between seropositive and seronegative groups of horses. Further analysis of associated markers could contribute to our understanding of anti-WNV defense mechanisms in horses." @default.
• W2937860281 created "2019-04-25" @default.
• W2937860281 creator A5012467555 @default.
• W2937860281 creator A5017940671 @default.
• W2937860281 creator A5028901723 @default.
• W2937860281 creator A5046437965 @default.
• W2937860281 creator A5047863283 @default.
• W2937860281 creator A5051648923 @default.
• W2937860281 creator A5059337585 @default.
• W2937860281 creator A5079817130 @default.
• W2937860281 creator A5090780248 @default.
• W2937860281 date "2019-06-01" @default.
• W2937860281 modified "2023-10-14" @default.
• W2937860281 title "Genetic susceptibility to West Nile virus infection in Camargue horses" @default.
• W2937860281 cites W1572786643 @default.
• W2937860281 cites W1801065823 @default.
• W2937860281 cites W1952983243 @default.
• W2937860281 cites W1967986717 @default.
• W2937860281 cites W1968788112 @default.
• W2937860281 cites W1979834448 @default.
• W2937860281 cites W1980233285 @default.
• W2937860281 cites W1980626076 @default.
• W2937860281 cites W1995405866 @default.
• W2937860281 cites W2004826140 @default.
• W2937860281 cites W2016563525 @default.
• W2937860281 cites W2018651329 @default.
• W2937860281 cites W2021655479 @default.
• W2937860281 cites W2024146289 @default.
• W2937860281 cites W2037825802 @default.
• W2937860281 cites W2039337280 @default.
• W2937860281 cites W2042420768 @default.
• W2937860281 cites W2044044562 @default.
• W2937860281 cites W2059254211 @default.
• W2937860281 cites W2061275021 @default.
• W2937860281 cites W2079974119 @default.
• W2937860281 cites W2081872599 @default.
• W2937860281 cites W2089335658 @default.
• W2937860281 cites W2090785343 @default.
• W2937860281 cites W2092363009 @default.
• W2937860281 cites W2096729929 @default.
• W2937860281 cites W2101934558 @default.
• W2937860281 cites W2108234281 @default.
• W2937860281 cites W2109298758 @default.
• W2937860281 cites W2117352205 @default.
• W2937860281 cites W2118911422 @default.
• W2937860281 cites W2123672726 @default.
• W2937860281 cites W2131271579 @default.
• W2937860281 cites W2136847298 @default.
• W2937860281 cites W2139794834 @default.
• W2937860281 cites W2140630012 @default.
• W2937860281 cites W2151045608 @default.
• W2937860281 cites W2156746746 @default.
• W2937860281 cites W2158214069 @default.
• W2937860281 cites W2161633633 @default.
• W2937860281 cites W2170664687 @default.
• W2937860281 cites W2170694569 @default.
• W2937860281 cites W2171429463 @default.
• W2937860281 cites W2195303995 @default.
• W2937860281 cites W2328300907 @default.
• W2937860281 cites W2403602008 @default.
• W2937860281 cites W2409267381 @default.
• W2937860281 cites W2523328969 @default.
• W2937860281 cites W2547690291 @default.
• W2937860281 cites W2565402777 @default.
• W2937860281 cites W2767582873 @default.
• W2937860281 cites W2788578140 @default.
• W2937860281 cites W2792865918 @default.
• W2937860281 cites W2793553466 @default.
• W2937860281 cites W2803932351 @default.
• W2937860281 cites W4246609039 @default.
• W2937860281 cites W4256243101 @default.
• W2937860281 doi "https://doi.org/10.1016/j.rvsc.2019.04.004" @default.
• W2937860281 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31005660" @default.
• W2937860281 hasPublicationYear "2019" @default.
• W2937860281 type Work @default.
• W2937860281 sameAs 2937860281 @default.
• W2937860281 citedByCount "7" @default.
• W2937860281 countsByYear W29378602812019 @default.
• W2937860281 countsByYear W29378602812020 @default.
• W2937860281 countsByYear W29378602812022 @default.
• W2937860281 countsByYear W29378602812023 @default.
• W2937860281 crossrefType "journal-article" @default.
• W2937860281 hasAuthorship W2937860281A5012467555 @default.
• W2937860281 hasAuthorship W2937860281A5017940671 @default.
• W2937860281 hasAuthorship W2937860281A5028901723 @default.
• W2937860281 hasAuthorship W2937860281A5046437965 @default.
• W2937860281 hasAuthorship W2937860281A5047863283 @default.
• W2937860281 hasAuthorship W2937860281A5051648923 @default.
• W2937860281 hasAuthorship W2937860281A5059337585 @default.
• W2937860281 hasAuthorship W2937860281A5079817130 @default.
• W2937860281 hasAuthorship W2937860281A5090780248 @default.
• W2937860281 hasConcept C104317684 @default.
• W2937860281 hasConcept C135763542 @default.
• W2937860281 hasConcept C153209595 @default.
• W2937860281 hasConcept C159047783 @default.
• W2937860281 hasConcept C2908647359 @default.
• W2937860281 hasConcept C31467283 @default.
• W2937860281 hasConcept C54355233 @default.

• next