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- W2938049908 abstract "Quantifying the brain's effective connectivity offers a unique window onto the causal architecture coupling the different regions of the brain. Here, we advocate a new, data-driven measure of directed (or effective) brain connectivity based on the recently developed information flow rate coefficient. The concept of the information flow rate is founded in the theory of stochastic dynamical systems and its derivation is based on first principles; unlike various commonly used linear and nonlinear correlations and empirical directional coefficients, the information flow rate can measure causal relations between time series with minimal assumptions. We apply the information flow rate to electroencephalography (EEG) signals in adolescent males to map out the directed, causal, spatial interactions between brain regions during resting-state conditions. To our knowledge, this is the first study of effective connectivity in the adolescent brain. Our analysis reveals that adolescents show a pattern of information flow that is strongly left lateralized, and consists of short and medium ranged bidirectional interactions across the frontal-central-temporal regions. These results suggest an intermediate state of brain maturation in adolescence." @default.
- W2938049908 created "2019-04-25" @default.
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- W2938049908 date "2019-04-13" @default.
- W2938049908 modified "2023-09-23" @default.
- W2938049908 title "Resting-state directed brain connectivity patterns in adolescents from source-reconstructed EEG signals based on information flow rate" @default.
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- W2938049908 doi "https://doi.org/10.1101/608299" @default.
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