FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2938135295> ?p ?o ?g. }

• W2938135295 endingPage "e0214733" @default.
• W2938135295 startingPage "e0214733" @default.
• W2938135295 abstract "The study aims to clarify the mechanism in patients with neurally mediated syncope (NMS), focusing on the adenylate cyclase (AC) activity level in lymphocytes. This study included 40 subjects: 22 healthy volunteers and 18 NMS patients. We investigated the changes in AC activity that occur during of syncope at rest and during the head-up tilt (HUT) test. We obtained 8 mL of blood at rest time and four times during the HUT test. Then, we measured the AC activity and the test reagent was added to the lymphocytes (10,000) and reacted for 30 min at room temperature. We were able to determine the standard value of AC activity when adrenaline (AD) and isoproterenol (IP) were added to lymphocytes. The results of our study showed one of the causes of NMS has a difference in AC activity level and classification of the patients into two different types of NMS was possible: either the vasodepressor type (VT) or mixed type (MT). At rest time, VT patients showed significantly higher AC activity (AD; 100 μM: p = 0.005, IP; 50 μM: p = 0.02) and MT patients showed significantly lower AC activity (AD; 10 μM: p = 0.02, IP; 50 μM: p = 0.004) than the average AC activity in healthy volunteers. Moreover, VT patients had significantly higher AC activity than healthy volunteers at the four points of the HUT test. MT patients had significantly lower AC activity (AD: p = 0.04 and IP: p = 0.04) than healthy volunteers at the rest time of HUT. Our study showed a significant difference in AC activities between NMS patients and healthy volunteers at rest. Therefore, a detailed NMS diagnosis can be made by examining AC activity levels in blood taken at rest time." @default.
• W2938135295 created "2019-04-25" @default.
• W2938135295 creator A5001915043 @default.
• W2938135295 creator A5024657243 @default.
• W2938135295 creator A5028354716 @default.
• W2938135295 creator A5031398993 @default.
• W2938135295 creator A5033860010 @default.
• W2938135295 creator A5034949085 @default.
• W2938135295 creator A5046932033 @default.
• W2938135295 creator A5058239639 @default.
• W2938135295 creator A5058903427 @default.
• W2938135295 date "2019-04-18" @default.
• W2938135295 modified "2023-09-24" @default.
• W2938135295 title "Neurally mediated syncope diagnosis based on adenylate cyclase activity in Japanese patients" @default.
• W2938135295 cites W1501613764 @default.
• W2938135295 cites W1517339234 @default.
• W2938135295 cites W1541290863 @default.
• W2938135295 cites W1557611662 @default.
• W2938135295 cites W1568427873 @default.
• W2938135295 cites W1760947721 @default.
• W2938135295 cites W182956740 @default.
• W2938135295 cites W192583731 @default.
• W2938135295 cites W1966244470 @default.
• W2938135295 cites W1970283298 @default.
• W2938135295 cites W1977148987 @default.
• W2938135295 cites W1977984619 @default.
• W2938135295 cites W1978271511 @default.
• W2938135295 cites W1980713816 @default.
• W2938135295 cites W1980956469 @default.
• W2938135295 cites W1981992194 @default.
• W2938135295 cites W1983657357 @default.
• W2938135295 cites W1998669669 @default.
• W2938135295 cites W2004147341 @default.
• W2938135295 cites W2005813077 @default.
• W2938135295 cites W2013162676 @default.
• W2938135295 cites W2016489131 @default.
• W2938135295 cites W2017810575 @default.
• W2938135295 cites W2027132208 @default.
• W2938135295 cites W2035366305 @default.
• W2938135295 cites W2042987473 @default.
• W2938135295 cites W2058796097 @default.
• W2938135295 cites W2062489228 @default.
• W2938135295 cites W2067415293 @default.
• W2938135295 cites W2077641788 @default.
• W2938135295 cites W2080419997 @default.
• W2938135295 cites W2081054223 @default.
• W2938135295 cites W2084073829 @default.
• W2938135295 cites W2096617955 @default.
• W2938135295 cites W2100094079 @default.
• W2938135295 cites W2105685328 @default.
• W2938135295 cites W2105951582 @default.
• W2938135295 cites W2109771867 @default.
• W2938135295 cites W2111757878 @default.
• W2938135295 cites W2119938349 @default.
• W2938135295 cites W2121774438 @default.
• W2938135295 cites W2125246627 @default.
• W2938135295 cites W2131245925 @default.
• W2938135295 cites W2132631818 @default.
• W2938135295 cites W2136203660 @default.
• W2938135295 cites W2137102729 @default.
• W2938135295 cites W2137558493 @default.
• W2938135295 cites W2138804049 @default.
• W2938135295 cites W2141860003 @default.
• W2938135295 cites W2154509682 @default.
• W2938135295 cites W2155547273 @default.
• W2938135295 cites W2159580288 @default.
• W2938135295 cites W2159693881 @default.
• W2938135295 cites W2165420119 @default.
• W2938135295 cites W2165806470 @default.
• W2938135295 cites W2170355588 @default.
• W2938135295 cites W2171967845 @default.
• W2938135295 cites W2196244048 @default.
• W2938135295 cites W2288937756 @default.
• W2938135295 cites W2336037318 @default.
• W2938135295 cites W2409923535 @default.
• W2938135295 cites W2414561396 @default.
• W2938135295 cites W2415978440 @default.
• W2938135295 cites W2561721860 @default.
• W2938135295 cites W4255337810 @default.
• W2938135295 doi "https://doi.org/10.1371/journal.pone.0214733" @default.
• W2938135295 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6472876" @default.
• W2938135295 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30998713" @default.
• W2938135295 hasPublicationYear "2019" @default.
• W2938135295 type Work @default.
• W2938135295 sameAs 2938135295 @default.
• W2938135295 citedByCount "5" @default.
• W2938135295 countsByYear W29381352952020 @default.
• W2938135295 countsByYear W29381352952021 @default.
• W2938135295 countsByYear W29381352952023 @default.
• W2938135295 crossrefType "journal-article" @default.
• W2938135295 hasAuthorship W2938135295A5001915043 @default.
• W2938135295 hasAuthorship W2938135295A5024657243 @default.
• W2938135295 hasAuthorship W2938135295A5028354716 @default.
• W2938135295 hasAuthorship W2938135295A5031398993 @default.
• W2938135295 hasAuthorship W2938135295A5033860010 @default.
• W2938135295 hasAuthorship W2938135295A5034949085 @default.
• W2938135295 hasAuthorship W2938135295A5046932033 @default.
• W2938135295 hasAuthorship W2938135295A5058239639 @default.

• next