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• W2938299969 abstract "An antibody-based immunotherapy for methamphetamine (MA) addictive treatment is has been drawing more and more attention in recent years. However, studies about methamphetamine antibody (anti-MA) immunodetections are rare, owing to the lack of immunogenicity of small molecule MA. This study provides a simple and effective approach to develop a convenient electrochemiluminescent (ECL) immunosensor for the testing of anti-MA. In short, the synthetic holoantigen of MA is immobilized on a homemade gold nanoparticles modified electrode as the sensing host for the specific recognition and detection of anti-MA. The research suggested, under optimal experimental conditions, the ECL intensity on resultant immunosensor has a wide-linear regression toward the anti-MA quantity within the range from 0.03 to 3.07 ng with a detection limit of 2.32 pg. It responded to the dosage of anti-MA in spiked blood samples with satisfactory recovery. According to the research, the developed sensor shows promise as a portable Anti-MA fast seized device which performs quickly and offers convenience, and will be helpful for forensic identification and clinical treatment." @default.
• W2938299969 created "2019-04-25" @default.
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• W2938299969 date "2019-04-12" @default.
• W2938299969 modified "2023-09-27" @default.
• W2938299969 title "A Convenient Electrochemiluminescent Immunosensor for Detecting Methamphetamine Antibody" @default.
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• W2938299969 doi "https://doi.org/10.2116/analsci.19p051" @default.
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