FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2938393802> ?p ?o ?g. }

• W2938393802 endingPage "308" @default.
• W2938393802 startingPage "308" @default.
• W2938393802 abstract "Measuring the magnitude of differentiation between populations based on genetic markers is commonplace in ecology, evolution, and conservation biology. The predominant differentiation metric used for this purpose is FST. Based on a qualitative survey, numerical analyses, simulations, and empirical data, I here argue that FST does not express the relationship to allele frequency differentiation between populations generally considered interpretable and desirable by researchers. In particular, FST (1) has low sensitivity when population differentiation is weak, (2) is contingent on the minor allele frequency across the populations, (3) can be strongly affected by asymmetry in sample sizes, and (4) can differ greatly among the available estimators. Together, these features can complicate pattern recognition and interpretation in population genetic and genomic analysis, as illustrated by empirical examples, and overall compromise the comparability of population differentiation among markers and study systems. I argue that a simple differentiation metric displaying intuitive properties, the absolute allele frequency difference AFD, provides a valuable alternative to FST. I provide a general definition of AFD applicable to both bi- and multi-allelic markers and conclude by making recommendations on the sample sizes needed to achieve robust differentiation estimates using AFD." @default.
• W2938393802 created "2019-04-25" @default.
• W2938393802 creator A5005311195 @default.
• W2938393802 date "2019-04-18" @default.
• W2938393802 modified "2023-09-30" @default.
• W2938393802 title "Allele Frequency Difference AFD–An Intuitive Alternative to FST for Quantifying Genetic Population Differentiation" @default.
• W2938393802 cites W1592777209 @default.
• W2938393802 cites W1776894899 @default.
• W2938393802 cites W1811495593 @default.
• W2938393802 cites W1830332211 @default.
• W2938393802 cites W1894118635 @default.
• W2938393802 cites W1908810753 @default.
• W2938393802 cites W1919772617 @default.
• W2938393802 cites W1939346899 @default.
• W2938393802 cites W1964227412 @default.
• W2938393802 cites W1964587468 @default.
• W2938393802 cites W1978569501 @default.
• W2938393802 cites W1988182864 @default.
• W2938393802 cites W1993835751 @default.
• W2938393802 cites W1997476591 @default.
• W2938393802 cites W2002682901 @default.
• W2938393802 cites W2033433285 @default.
• W2938393802 cites W2045518901 @default.
• W2938393802 cites W2051332263 @default.
• W2938393802 cites W2075923653 @default.
• W2938393802 cites W2078663788 @default.
• W2938393802 cites W2083239248 @default.
• W2938393802 cites W2090237601 @default.
• W2938393802 cites W2092092816 @default.
• W2938393802 cites W2093688842 @default.
• W2938393802 cites W2096009187 @default.
• W2938393802 cites W2097556417 @default.
• W2938393802 cites W2106791022 @default.
• W2938393802 cites W2107391749 @default.
• W2938393802 cites W2107735615 @default.
• W2938393802 cites W2108881580 @default.
• W2938393802 cites W2112799266 @default.
• W2938393802 cites W2114709340 @default.
• W2938393802 cites W2123943890 @default.
• W2938393802 cites W2126870214 @default.
• W2938393802 cites W2132297696 @default.
• W2938393802 cites W2138902064 @default.
• W2938393802 cites W2148296862 @default.
• W2938393802 cites W2149421560 @default.
• W2938393802 cites W2152613935 @default.
• W2938393802 cites W2157770413 @default.
• W2938393802 cites W2158751030 @default.
• W2938393802 cites W2164346385 @default.
• W2938393802 cites W2165020864 @default.
• W2938393802 cites W2167067208 @default.
• W2938393802 cites W2168024937 @default.
• W2938393802 cites W2168129076 @default.
• W2938393802 cites W2168526163 @default.
• W2938393802 cites W2180675910 @default.
• W2938393802 cites W2213112864 @default.
• W2938393802 cites W2272072181 @default.
• W2938393802 cites W2330435311 @default.
• W2938393802 cites W2411963812 @default.
• W2938393802 cites W2550845433 @default.
• W2938393802 cites W2586026889 @default.
• W2938393802 cites W2767834706 @default.
• W2938393802 cites W2781714584 @default.
• W2938393802 cites W2887065873 @default.
• W2938393802 cites W2907575781 @default.
• W2938393802 cites W2913353941 @default.
• W2938393802 cites W2953283624 @default.
• W2938393802 cites W597540994 @default.
• W2938393802 doi "https://doi.org/10.3390/genes10040308" @default.
• W2938393802 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6523497" @default.
• W2938393802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31003563" @default.
• W2938393802 hasPublicationYear "2019" @default.
• W2938393802 type Work @default.
• W2938393802 sameAs 2938393802 @default.
• W2938393802 citedByCount "40" @default.
• W2938393802 countsByYear W29383938022019 @default.
• W2938393802 countsByYear W29383938022020 @default.
• W2938393802 countsByYear W29383938022021 @default.
• W2938393802 countsByYear W29383938022022 @default.
• W2938393802 countsByYear W29383938022023 @default.
• W2938393802 crossrefType "journal-article" @default.
• W2938393802 hasAuthorship W2938393802A5005311195 @default.
• W2938393802 hasBestOaLocation W29383938021 @default.
• W2938393802 hasConcept C104317684 @default.
• W2938393802 hasConcept C105795698 @default.
• W2938393802 hasConcept C114614502 @default.
• W2938393802 hasConcept C144024400 @default.
• W2938393802 hasConcept C149923435 @default.
• W2938393802 hasConcept C162324750 @default.
• W2938393802 hasConcept C176217482 @default.
• W2938393802 hasConcept C180754005 @default.
• W2938393802 hasConcept C185429906 @default.
• W2938393802 hasConcept C197947376 @default.
• W2938393802 hasConcept C21547014 @default.
• W2938393802 hasConcept C2908647359 @default.
• W2938393802 hasConcept C33923547 @default.
• W2938393802 hasConcept C37463918 @default.
• W2938393802 hasConcept C54355233 @default.
• W2938393802 hasConcept C78458016 @default.

• next