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- W2938396170 abstract "Summary Many types of RNA s, including messenger RNA s ( mRNA s), long noncoding RNA s (lnc RNA s) and circular RNA s (circ RNA s), play crucial roles in regulating fat cell differentiation and tissue development. However, the expression profiles of these RNA s in different adipose tissues are still largely unknown. To shed light on this issue, we performed a transcriptome analysis of mRNA s, lnc RNA s and circ RNA s obtained from intramuscular adipose tissue, subcutaneous adipose tissue, retroperitoneal adipose tissue and mesenteric adipose tissue of Chinese Erhualian pigs. A number of differentially expressed mRNA s, lnc RNA s and circ RNA s were identified among the four adipose tissues. Tissue‐specific analysis indicated that circ RNA s exhibited the highest tissue specificity among mRNA s, lnc RNA s and circ RNA s, whereas intramuscular adipose tissue had the most tissue‐specific genes among the four adipose tissues. Gene Ontology analysis showed that differentially expressed mRNA s among groups were involved mainly in lipid metabolism and immune inflammatory response processes. Furthermore, the co‐expression network construction of mRNA s–lnc RNA s revealed that several important lnc RNA s, such as MSTRG .426159 and MSTRG .604206, might associate with lipid metabolic process. Taken together, these data provide a genome‐wide resource of mRNA s, lnc RNA s and circ RNA s potentially involved in porcine fat metabolism, thus improving understanding of their function in diverse adipose tissues." @default.
- W2938396170 created "2019-04-25" @default.
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- W2938396170 date "2019-04-14" @default.
- W2938396170 modified "2023-10-18" @default.
- W2938396170 title "Genome‐wide identification and comparison of <scp>mRNA</scp> s, lnc <scp>RNA</scp> s and circ <scp>RNA</scp> s in porcine intramuscular, subcutaneous, retroperitoneal and mesenteric adipose tissues" @default.
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- W2938396170 doi "https://doi.org/10.1111/age.12781" @default.
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