Matches in SemOpenAlex for { <https://semopenalex.org/work/W2938409008> ?p ?o ?g. }
Showing items 1 to 52 of
52
with 100 items per page.
- W2938409008 abstract "Introduction: Metastasis to bone marrow by solid malignancies is a rare event and it upgrades the tumor thereby worsening the prognosis. This is caused by an impaired response to therapy and other manifestation resulting from decreased hematopoiesis. The common malignancies to metastasize in male and female are carcinoma prostate and carcinoma breast, respectively. It is noted that metastasis from small round cell tumor (SRCT) predominates in children. Here, we present a series of cases of bone marrow metastasis by solid organ malignancies over a period of 5 years.Objectives: The aim of this study was to investigate the clinical and hematological characteristics of patients with BM metastases of solid tumors diagnosed by bone marrow (BM) aspiration.Materials & methods: In this study, we reviewed 3520 bone marrow aspirates in our hospital from January 2013 to December 2017. Patients diagnosed with solid malignancies metastasizing to bone marrow were selected.Results: We found a total of 26 cases of solid malignancies with metastasis to bone marrow. The age of the patients ranged from 2–88 years (mean age of 46 years). Most of the patients were adults (19/26), of which 77.7% were males. Seven of the 26 patients were in the pediatric age group, with an age range of 2-11 years. Various malignancies metastasizing to marrow were evaluated and clinical and hematological correlation was done. The common presenting sign & symptoms were fever, anorexia and bodyache and organomegaly. Anemia was the most common hematological finding at the time of admission. Carcinoma prostate was the most common metastatic tumor in adults and small round cell tumor in children.Conclusion: BM is one of the important and infrequent sites of metastasis of solid tumors. Detection of bone marrow metastasis has significant clinical implication with impact on therapeutic decisions and is associated with poor prognosis. Aspiration of the BM provides an easy and quick way of detecting involvement, however, biopsy with immunohistochemical and/or molecular techniques may be needed in case of microscopical tumor burden." @default.
- W2938409008 created "2019-04-25" @default.
- W2938409008 creator A5010933336 @default.
- W2938409008 creator A5038781721 @default.
- W2938409008 creator A5041489854 @default.
- W2938409008 creator A5077467749 @default.
- W2938409008 creator A5079302175 @default.
- W2938409008 date "2019-03-16" @default.
- W2938409008 modified "2023-09-28" @default.
- W2938409008 title "Bone Marrow Cytomorphology And Clinico-Hematological Profile of Metastatic Solid Tumors: A 5-Year Audit from A Tertiary Care Centre in Northern India" @default.
- W2938409008 doi "https://doi.org/10.21276/apalm.2290" @default.
- W2938409008 hasPublicationYear "2019" @default.
- W2938409008 type Work @default.
- W2938409008 sameAs 2938409008 @default.
- W2938409008 citedByCount "0" @default.
- W2938409008 crossrefType "journal-article" @default.
- W2938409008 hasAuthorship W2938409008A5010933336 @default.
- W2938409008 hasAuthorship W2938409008A5038781721 @default.
- W2938409008 hasAuthorship W2938409008A5041489854 @default.
- W2938409008 hasAuthorship W2938409008A5077467749 @default.
- W2938409008 hasAuthorship W2938409008A5079302175 @default.
- W2938409008 hasBestOaLocation W29384090081 @default.
- W2938409008 hasConcept C121608353 @default.
- W2938409008 hasConcept C126322002 @default.
- W2938409008 hasConcept C142724271 @default.
- W2938409008 hasConcept C143998085 @default.
- W2938409008 hasConcept C2777546739 @default.
- W2938409008 hasConcept C2777783956 @default.
- W2938409008 hasConcept C2778248108 @default.
- W2938409008 hasConcept C2779013556 @default.
- W2938409008 hasConcept C2779975986 @default.
- W2938409008 hasConcept C2780007613 @default.
- W2938409008 hasConcept C71924100 @default.
- W2938409008 hasConceptScore W2938409008C121608353 @default.
- W2938409008 hasConceptScore W2938409008C126322002 @default.
- W2938409008 hasConceptScore W2938409008C142724271 @default.
- W2938409008 hasConceptScore W2938409008C143998085 @default.
- W2938409008 hasConceptScore W2938409008C2777546739 @default.
- W2938409008 hasConceptScore W2938409008C2777783956 @default.
- W2938409008 hasConceptScore W2938409008C2778248108 @default.
- W2938409008 hasConceptScore W2938409008C2779013556 @default.
- W2938409008 hasConceptScore W2938409008C2779975986 @default.
- W2938409008 hasConceptScore W2938409008C2780007613 @default.
- W2938409008 hasConceptScore W2938409008C71924100 @default.
- W2938409008 hasLocation W29384090081 @default.
- W2938409008 hasLocation W29384090082 @default.
- W2938409008 hasOpenAccess W2938409008 @default.
- W2938409008 hasPrimaryLocation W29384090081 @default.
- W2938409008 isParatext "false" @default.
- W2938409008 isRetracted "false" @default.
- W2938409008 magId "2938409008" @default.
- W2938409008 workType "article" @default.