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- W2938472019 abstract "Proteomics and metabolomics are emerging and powerful tools to unravel the complex molecular mechanisms regulating reproduction in male fish. So far, numerous proteins and metabolites have been identified that provide us with valuable information to conduct a comprehensive analysis on seminal plasma and spermatozoa components and their functions. These analyses have allowed a better understanding of the blood-testis barrier functions, the molecular mechanisms underlying spermatogenesis, spermatozoa maturation, motility signaling, and competition as well as the mechanism of cryodamage to sperm structure and functions. To extend, proteins that undergo posttranslational modification, such as phosphorylation and oxidation in response to spermatozoa motility activation and cryopreservation, respectively, have been identified. Proteomic studies resulted in identification of potential proteins that can be used as biomarkers for sperm quality and freezability to enable the control of artificial reproduction, and to improve methods for long-term preservation (cryopreservation) of sperm. The different proteins expressed in the spermatozoa of neomales and normal males can also provide new insights into development of methods for separating X and Y fish sperm, and changes in the protein profiles in haploid and diploid spermatozoa will provide new perspectives to better understand the mechanism of male polyploidy. Overall, the knowledge gained by proteomic and metabolomic studies is important from basic to applied sciences for the development and/or optimisation of techniques in controlled fish reproduction." @default.
- W2938472019 created "2019-04-25" @default.
- W2938472019 creator A5038626702 @default.
- W2938472019 creator A5047804821 @default.
- W2938472019 creator A5075122679 @default.
- W2938472019 date "2019-07-01" @default.
- W2938472019 modified "2023-10-18" @default.
- W2938472019 title "Proteomic and metabolomic insights into the functions of the male reproductive system in fishes" @default.
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