Matches in SemOpenAlex for { <https://semopenalex.org/work/W2938477360> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2938477360 endingPage "619" @default.
- W2938477360 startingPage "607" @default.
- W2938477360 abstract "New quinazoline derivatives were prepared by one pot reaction of anthranilic acid, acetic anhydride and primary amines, under ultrasonic irradiation. As a result, Ultrasonic irradiation has led to affordable, clean synthesis of a variety of target compounds in much higher yields, than traditional methods. This method has numerous advantages: such as higher yields, shorter reactions time, and easier work-up. Several structural classes among these compounds were identified to have vasorelaxant activity. In this respect, all of the newly synthesized quinazolinone derivatives displayed vasorelaxant properties on the isolated thoracic rat aorta. The IC50 of compounds 2a (-6.00 ± 0.55), 2g (-7.31 ± 0.94), 2n (-7.15 ± 0.81) and 2p (-7.77 ± 0.31) was comparable to that seen in the Acetylcholine (-7.13 ± 0.14). The structures of the newly synthesized compounds were confirmed by IR, 1H NMR, 13C NMR, mass spectral studies, elemental analysis, and melting point." @default.
- W2938477360 created "2019-04-25" @default.
- W2938477360 creator A5001845830 @default.
- W2938477360 creator A5018710843 @default.
- W2938477360 creator A5036997411 @default.
- W2938477360 creator A5037479898 @default.
- W2938477360 creator A5048717412 @default.
- W2938477360 creator A5090720176 @default.
- W2938477360 date "2019-01-01" @default.
- W2938477360 modified "2023-09-23" @default.
- W2938477360 title "Highly Efficient, One Pot, Solvent and Catalyst, Free Synthesis of Novel Quinazoline Derivatives under Ultrasonic Irradiation and Their Vasorelaxant Activity Isolated Thoracic Aorta of Rat." @default.
- W2938477360 cites W1987647090 @default.
- W2938477360 cites W1995287083 @default.
- W2938477360 cites W2021220760 @default.
- W2938477360 cites W2024051712 @default.
- W2938477360 cites W2031731984 @default.
- W2938477360 cites W2036508105 @default.
- W2938477360 cites W2059708411 @default.
- W2938477360 cites W2080829709 @default.
- W2938477360 cites W2094606553 @default.
- W2938477360 cites W2156663340 @default.
- W2938477360 cites W2172257436 @default.
- W2938477360 cites W2214008998 @default.
- W2938477360 cites W2412419799 @default.
- W2938477360 cites W2949144434 @default.
- W2938477360 doi "https://doi.org/10.22037/ijpr.2019.1100675" @default.
- W2938477360 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6706738" @default.
- W2938477360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31531045" @default.
- W2938477360 hasPublicationYear "2019" @default.
- W2938477360 type Work @default.
- W2938477360 sameAs 2938477360 @default.
- W2938477360 citedByCount "2" @default.
- W2938477360 countsByYear W29384773602020 @default.
- W2938477360 countsByYear W29384773602022 @default.
- W2938477360 crossrefType "journal-article" @default.
- W2938477360 hasAuthorship W2938477360A5001845830 @default.
- W2938477360 hasAuthorship W2938477360A5018710843 @default.
- W2938477360 hasAuthorship W2938477360A5036997411 @default.
- W2938477360 hasAuthorship W2938477360A5037479898 @default.
- W2938477360 hasAuthorship W2938477360A5048717412 @default.
- W2938477360 hasAuthorship W2938477360A5090720176 @default.
- W2938477360 hasConcept C13530604 @default.
- W2938477360 hasConcept C13965031 @default.
- W2938477360 hasConcept C161790260 @default.
- W2938477360 hasConcept C178790620 @default.
- W2938477360 hasConcept C185592680 @default.
- W2938477360 hasConcept C2777162773 @default.
- W2938477360 hasConcept C2778866207 @default.
- W2938477360 hasConcept C2779816182 @default.
- W2938477360 hasConcept C2779854550 @default.
- W2938477360 hasConcept C2780471494 @default.
- W2938477360 hasConcept C64885871 @default.
- W2938477360 hasConceptScore W2938477360C13530604 @default.
- W2938477360 hasConceptScore W2938477360C13965031 @default.
- W2938477360 hasConceptScore W2938477360C161790260 @default.
- W2938477360 hasConceptScore W2938477360C178790620 @default.
- W2938477360 hasConceptScore W2938477360C185592680 @default.
- W2938477360 hasConceptScore W2938477360C2777162773 @default.
- W2938477360 hasConceptScore W2938477360C2778866207 @default.
- W2938477360 hasConceptScore W2938477360C2779816182 @default.
- W2938477360 hasConceptScore W2938477360C2779854550 @default.
- W2938477360 hasConceptScore W2938477360C2780471494 @default.
- W2938477360 hasConceptScore W2938477360C64885871 @default.
- W2938477360 hasIssue "2" @default.
- W2938477360 hasLocation W29384773601 @default.
- W2938477360 hasOpenAccess W2938477360 @default.
- W2938477360 hasPrimaryLocation W29384773601 @default.
- W2938477360 hasRelatedWork W2184665476 @default.
- W2938477360 hasRelatedWork W2528983204 @default.
- W2938477360 hasRelatedWork W2938477360 @default.
- W2938477360 hasRelatedWork W2952653827 @default.
- W2938477360 hasRelatedWork W2952761898 @default.
- W2938477360 hasRelatedWork W2182184680 @default.
- W2938477360 hasRelatedWork W2183341839 @default.
- W2938477360 hasRelatedWork W2463068670 @default.
- W2938477360 hasRelatedWork W2611523674 @default.
- W2938477360 hasRelatedWork W2791042596 @default.
- W2938477360 hasVolume "18" @default.
- W2938477360 isParatext "false" @default.
- W2938477360 isRetracted "false" @default.
- W2938477360 magId "2938477360" @default.
- W2938477360 workType "article" @default.