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- W2938573684 abstract "Summary Glutaminyl‐peptide cyclotransferase‐like ( QPCTL ) is an isoenzyme of glutaminyl‐peptide cyclotransferase ( QPCT ). QPCTL and QPCT catalyze the formation of N‐terminal modified pyroglutamate‐fractalkine and the chemokine CCL 2. The objective of this study was to investigate the association between insertions/deletions in the chicken QPCTL promoter region with growth traits in chickens. We first detected two insertion/deletion variants of QPCTL via whole‐genome resequencing analysis of DNA samples from Xichuan chickens. A total of 1896 individuals from 12 breeds were genotyped for 52‐ and 224‐bp insertions/deletions. We found two novel insertions/deletions in the promoter region of the chicken QPCTL gene and studied their association with chicken body weight and carcass traits. Our findings show that QPCTL can be a molecular marker for chicken genetics and breeding programs." @default.
- W2938573684 created "2019-04-25" @default.
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- W2938573684 date "2019-04-11" @default.
- W2938573684 modified "2023-10-13" @default.
- W2938573684 title "Two insertion/deletion variants in the promoter region of the <i> <scp>QPCTL</scp> </i> gene are significantly associated with body weight and carcass traits in chickens" @default.
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- W2938573684 doi "https://doi.org/10.1111/age.12741" @default.
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