Matches in SemOpenAlex for { <https://semopenalex.org/work/W2938598156> ?p ?o ?g. }
- W2938598156 abstract "The significant biochemical and physiological effects of psychological stress are beginning to be recognized as exacerbating common diseases, including osteoporosis. This review discusses the current evidence for psychological stress-associated mental health disorders as risk factors for osteoporosis, the mechanisms that may link these conditions, and potential implications for treatment. Traditional, alternative, and adjunctive therapies are discussed. This review is not intended to provide therapeutic recommendations, but, rather, the goal of this review is to delineate potential interactions of psychological stress and osteoporosis and to highlight potential multi-system implications of pharmacological interventions. Review of the current literature identifies several potentially overlapping mechanistic pathways that may be of interest (e.g., glucocorticoid signaling, insulin-like growth factor signaling, serotonin signaling) for further basic and clinical research. Current literature also supports the potential for cross-effects of therapeutics for osteoporosis and mental health disorders. While studies examining a direct link between osteoporosis and chronic psychological stress are limited, the studies reviewed herein suggest that a multi-factorial, personalized approach should be considered for improved patient outcomes in populations experiencing psychological stress, particularly those at high-risk for development of osteoporosis." @default.
- W2938598156 created "2019-04-25" @default.
- W2938598156 creator A5022996563 @default.
- W2938598156 creator A5032755593 @default.
- W2938598156 creator A5047082878 @default.
- W2938598156 creator A5051928690 @default.
- W2938598156 creator A5073645128 @default.
- W2938598156 date "2019-04-09" @default.
- W2938598156 modified "2023-10-09" @default.
- W2938598156 title "Impacts of Psychological Stress on Osteoporosis: Clinical Implications and Treatment Interactions" @default.
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