FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2938722712> ?p ?o ?g. }

• W2938722712 endingPage "357" @default.
• W2938722712 startingPage "348" @default.
• W2938722712 abstract "Rosai-Dorfman disease is a rare subtype of non-Langerhans cell histiocytosis. With the last major report published in 1990, there is a paucity of contemporary data on this disease. Our objective was to report the clinicopathological features, treatments and outcomes of patients seen at a tertiary referral center. Sixty-four patients with histopathological diagnosis of Rosai-Dorfman disease were identified from 1994 to 2017 (median age 50 years; range, 2-79). The median duration from symptom onset to diagnosis was seven months (range, 0-128), which was also reflected in the number of biopsies required to establish the diagnosis (median 2; range, 1-6). The most common presentation was subcutaneous masses (40%). Of the 64 patients, 8% had classical (nodal only) and 92% had extra-nodal disease (67% extra-nodal only). The most common organs involved were skin and subcutaneous tissue (52%), followed by lymph nodes (33%). Three patients had an overlap with Erdheim-Chester disease, which had not been described before. Two of these were found to have MAP2K1 mutations. Commonly utilized first line treatments were surgical excision (38%) and systemic corticosteroids (27%). Corticosteroids led to a response in 56% of the cases. Of those treated initially, 15 (30%) patients developed recurrent disease. The most commonly used systemic agent was cladribine (n=6), with 67% overall response rate. Our study demonstrates that Rosai-Dorfman disease has diverse clinical manifestations and outcomes. While this disease has been historically considered a benign entity, a subset of patients endures an aggressive course necessitating the use of systemic therapies." @default.
• W2938722712 created "2019-04-25" @default.
• W2938722712 creator A5009747339 @default.
• W2938722712 creator A5013824370 @default.
• W2938722712 creator A5020872528 @default.
• W2938722712 creator A5025688165 @default.
• W2938722712 creator A5029802364 @default.
• W2938722712 creator A5034893907 @default.
• W2938722712 creator A5056210769 @default.
• W2938722712 creator A5061713890 @default.
• W2938722712 creator A5069952110 @default.
• W2938722712 creator A5072463255 @default.
• W2938722712 creator A5080184636 @default.
• W2938722712 creator A5081170659 @default.
• W2938722712 creator A5088357128 @default.
• W2938722712 creator A5090092577 @default.
• W2938722712 date "2019-04-19" @default.
• W2938722712 modified "2023-10-14" @default.
• W2938722712 title "Clinicopathological features, treatment approaches, and outcomes in Rosai-Dorfman disease" @default.
• W2938722712 cites W1564363191 @default.
• W2938722712 cites W16222215 @default.
• W2938722712 cites W1794966075 @default.
• W2938722712 cites W1864344361 @default.
• W2938722712 cites W19653836 @default.
• W2938722712 cites W1967907163 @default.
• W2938722712 cites W1973230735 @default.
• W2938722712 cites W1980231715 @default.
• W2938722712 cites W2012323565 @default.
• W2938722712 cites W2020637027 @default.
• W2938722712 cites W2027269189 @default.
• W2938722712 cites W2027620575 @default.
• W2938722712 cites W2045372770 @default.
• W2938722712 cites W2048765718 @default.
• W2938722712 cites W2065471640 @default.
• W2938722712 cites W2076746365 @default.
• W2938722712 cites W2113614349 @default.
• W2938722712 cites W2115632011 @default.
• W2938722712 cites W2139689307 @default.
• W2938722712 cites W2152107082 @default.
• W2938722712 cites W2160981405 @default.
• W2938722712 cites W2234683072 @default.
• W2938722712 cites W2284565720 @default.
• W2938722712 cites W2409258773 @default.
• W2938722712 cites W2419245869 @default.
• W2938722712 cites W2593045216 @default.
• W2938722712 cites W2624399308 @default.
• W2938722712 cites W2730295253 @default.
• W2938722712 cites W2765636729 @default.
• W2938722712 cites W2774432730 @default.
• W2938722712 cites W2802582740 @default.
• W2938722712 cites W2804412041 @default.
• W2938722712 cites W2809519364 @default.
• W2938722712 cites W2913946275 @default.
• W2938722712 cites W2921153272 @default.
• W2938722712 doi "https://doi.org/10.3324/haematol.2019.219626" @default.
• W2938722712 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7012468" @default.
• W2938722712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31004029" @default.
• W2938722712 hasPublicationYear "2019" @default.
• W2938722712 type Work @default.
• W2938722712 sameAs 2938722712 @default.
• W2938722712 citedByCount "90" @default.
• W2938722712 countsByYear W29387227122019 @default.
• W2938722712 countsByYear W29387227122020 @default.
• W2938722712 countsByYear W29387227122021 @default.
• W2938722712 countsByYear W29387227122022 @default.
• W2938722712 countsByYear W29387227122023 @default.
• W2938722712 crossrefType "journal-article" @default.
• W2938722712 hasAuthorship W2938722712A5009747339 @default.
• W2938722712 hasAuthorship W2938722712A5013824370 @default.
• W2938722712 hasAuthorship W2938722712A5020872528 @default.
• W2938722712 hasAuthorship W2938722712A5025688165 @default.
• W2938722712 hasAuthorship W2938722712A5029802364 @default.
• W2938722712 hasAuthorship W2938722712A5034893907 @default.
• W2938722712 hasAuthorship W2938722712A5056210769 @default.
• W2938722712 hasAuthorship W2938722712A5061713890 @default.
• W2938722712 hasAuthorship W2938722712A5069952110 @default.
• W2938722712 hasAuthorship W2938722712A5072463255 @default.
• W2938722712 hasAuthorship W2938722712A5080184636 @default.
• W2938722712 hasAuthorship W2938722712A5081170659 @default.
• W2938722712 hasAuthorship W2938722712A5088357128 @default.
• W2938722712 hasAuthorship W2938722712A5090092577 @default.
• W2938722712 hasBestOaLocation W29387227121 @default.
• W2938722712 hasConcept C126322002 @default.
• W2938722712 hasConcept C16005928 @default.
• W2938722712 hasConcept C2779134260 @default.
• W2938722712 hasConcept C2781192723 @default.
• W2938722712 hasConcept C71924100 @default.
• W2938722712 hasConceptScore W2938722712C126322002 @default.
• W2938722712 hasConceptScore W2938722712C16005928 @default.
• W2938722712 hasConceptScore W2938722712C2779134260 @default.
• W2938722712 hasConceptScore W2938722712C2781192723 @default.
• W2938722712 hasConceptScore W2938722712C71924100 @default.
• W2938722712 hasIssue "2" @default.
• W2938722712 hasLocation W29387227121 @default.
• W2938722712 hasLocation W29387227122 @default.
• W2938722712 hasLocation W29387227123 @default.
• W2938722712 hasOpenAccess W2938722712 @default.
• W2938722712 hasPrimaryLocation W29387227121 @default.

• next