Matches in SemOpenAlex for { <https://semopenalex.org/work/W2938746902> ?p ?o ?g. }
- W2938746902 endingPage "126" @default.
- W2938746902 startingPage "114" @default.
- W2938746902 abstract "Critical congenital heart disease (cCHD) is the most common reason for acute cardiac failure in the neonatal period. cCHD, defined by systemic low cardiac output (LCO) and requiring surgery or catheter-based intervention in the first year of life, has an incidence of approximately 15% of CHD and is responsible for up to 25% fatalities of newborn infants. Clinical deterioration develops in most cases due to rapid closure of the ductus arteriosus (DA). Early diagnosis and immediate treatment determinate beneficial outcome. Critical CHD can be classified in duct-dependent systemic flow, duct-dependent pulmonary flow and transposition of the great arteries. The latter two manifest themselves in oxygen resistant cyanosis, whereas CHD with duct-dependent systemic flow may present itself with cardiogenic shock, which can be difficult to differentiate from other causes of shock such as sepsis. Besides prostaglandin therapy for reopening the arterial duct, a balanced parallel pulmonary and systemic circulation should be a therapeutic goal. In CHD with duct-dependent systemic flow a decrease of pulmonary resistance should be avoided; therefore inadequate oxygen therapy, hyperventilation and alkalosis due to excessive treatment of acidosis, should be averted. Volume therapy should be performed carefully. In CHD with duct-dependent pulmonary flow, pulmonary resistance can be decreased, in case of poor pulmonary flow systemic resistance should be increased, mild alkalosis is recommended. Intense volume therapy is in most cases necessary, except if a restrictive atrial communication is present. In addition to intensive care measures, an arsenal of catheter- and surgery-based procedures need to be hold available as back-up for emergency procedures. Transcatheter interventions are nowadays decisive. Atrial-septostomy was the first and still the most utilized high-urgency procedure; DA-stenting is used in prostaglandin-refractory duct stenosis. In the presence of critical aortic valve stenosis, palliation consists of balloon valvuloplasty. In critical aortic coarctation with myocardial failure and no response to prostaglandin, palliative balloon angioplasty may be the method of choice as bridging for corrective surgery." @default.
- W2938746902 created "2019-04-25" @default.
- W2938746902 creator A5002636901 @default.
- W2938746902 creator A5016727630 @default.
- W2938746902 creator A5053507144 @default.
- W2938746902 creator A5064182272 @default.
- W2938746902 creator A5069037562 @default.
- W2938746902 creator A5090411081 @default.
- W2938746902 date "2019-04-01" @default.
- W2938746902 modified "2023-10-02" @default.
- W2938746902 title "Acute therapy of newborns with critical congenital heart disease" @default.
- W2938746902 cites W1963997841 @default.
- W2938746902 cites W1969243335 @default.
- W2938746902 cites W1972031538 @default.
- W2938746902 cites W1977954359 @default.
- W2938746902 cites W1986676875 @default.
- W2938746902 cites W2012517517 @default.
- W2938746902 cites W2030666489 @default.
- W2938746902 cites W2057199085 @default.
- W2938746902 cites W2060202593 @default.
- W2938746902 cites W2063763041 @default.
- W2938746902 cites W2063844574 @default.
- W2938746902 cites W2066085179 @default.
- W2938746902 cites W2069063448 @default.
- W2938746902 cites W2089743535 @default.
- W2938746902 cites W2098138625 @default.
- W2938746902 cites W2101757361 @default.
- W2938746902 cites W2114764052 @default.
- W2938746902 cites W2135242378 @default.
- W2938746902 cites W2156984851 @default.
- W2938746902 cites W2166474541 @default.
- W2938746902 cites W2318557035 @default.
- W2938746902 cites W2412685097 @default.
- W2938746902 cites W2516846155 @default.
- W2938746902 cites W2614781785 @default.
- W2938746902 cites W2751965027 @default.
- W2938746902 cites W2769738424 @default.
- W2938746902 cites W2772775915 @default.
- W2938746902 cites W2801620877 @default.
- W2938746902 cites W4239270515 @default.
- W2938746902 cites W52382270 @default.
- W2938746902 doi "https://doi.org/10.21037/tp.2019.04.06" @default.
- W2938746902 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6514285" @default.
- W2938746902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31161078" @default.
- W2938746902 hasPublicationYear "2019" @default.
- W2938746902 type Work @default.
- W2938746902 sameAs 2938746902 @default.
- W2938746902 citedByCount "26" @default.
- W2938746902 countsByYear W29387469022020 @default.
- W2938746902 countsByYear W29387469022021 @default.
- W2938746902 countsByYear W29387469022022 @default.
- W2938746902 countsByYear W29387469022023 @default.
- W2938746902 crossrefType "journal-article" @default.
- W2938746902 hasAuthorship W2938746902A5002636901 @default.
- W2938746902 hasAuthorship W2938746902A5016727630 @default.
- W2938746902 hasAuthorship W2938746902A5053507144 @default.
- W2938746902 hasAuthorship W2938746902A5064182272 @default.
- W2938746902 hasAuthorship W2938746902A5069037562 @default.
- W2938746902 hasAuthorship W2938746902A5090411081 @default.
- W2938746902 hasBestOaLocation W29387469021 @default.
- W2938746902 hasConcept C126322002 @default.
- W2938746902 hasConcept C164705383 @default.
- W2938746902 hasConcept C177713679 @default.
- W2938746902 hasConcept C178853913 @default.
- W2938746902 hasConcept C2776064143 @default.
- W2938746902 hasConcept C2776850375 @default.
- W2938746902 hasConcept C2778384902 @default.
- W2938746902 hasConcept C2780074459 @default.
- W2938746902 hasConcept C2781236024 @default.
- W2938746902 hasConcept C500558357 @default.
- W2938746902 hasConcept C58245268 @default.
- W2938746902 hasConcept C71924100 @default.
- W2938746902 hasConceptScore W2938746902C126322002 @default.
- W2938746902 hasConceptScore W2938746902C164705383 @default.
- W2938746902 hasConceptScore W2938746902C177713679 @default.
- W2938746902 hasConceptScore W2938746902C178853913 @default.
- W2938746902 hasConceptScore W2938746902C2776064143 @default.
- W2938746902 hasConceptScore W2938746902C2776850375 @default.
- W2938746902 hasConceptScore W2938746902C2778384902 @default.
- W2938746902 hasConceptScore W2938746902C2780074459 @default.
- W2938746902 hasConceptScore W2938746902C2781236024 @default.
- W2938746902 hasConceptScore W2938746902C500558357 @default.
- W2938746902 hasConceptScore W2938746902C58245268 @default.
- W2938746902 hasConceptScore W2938746902C71924100 @default.
- W2938746902 hasIssue "2" @default.
- W2938746902 hasLocation W29387469021 @default.
- W2938746902 hasLocation W29387469022 @default.
- W2938746902 hasLocation W29387469023 @default.
- W2938746902 hasLocation W29387469024 @default.
- W2938746902 hasOpenAccess W2938746902 @default.
- W2938746902 hasPrimaryLocation W29387469021 @default.
- W2938746902 hasRelatedWork W1564625007 @default.
- W2938746902 hasRelatedWork W1895434829 @default.
- W2938746902 hasRelatedWork W1978545412 @default.
- W2938746902 hasRelatedWork W2015137819 @default.
- W2938746902 hasRelatedWork W203695840 @default.
- W2938746902 hasRelatedWork W2349413564 @default.
- W2938746902 hasRelatedWork W2421448364 @default.