Matches in SemOpenAlex for { <https://semopenalex.org/work/W2938813031> ?p ?o ?g. }
- W2938813031 abstract "Older adults often suffer from age- and behavior-related brain changes affecting neuronal functioning and, therefore, cognitive and motor functions. The improvement of these functions might decrease falls and improve mobility. Previous studies indicate that video game-based physical exercise, so-called exergames, or omega-3 fatty acids (FAs) improve motor and cognitive functioning through brain adaptations. The aim of this study was to assess the effects of exergame training combined with fish oil supplementation on neuronal system levels in the brain and behavioral measurements in older adults. We hypothesized that the combination would differently affect these factors compared to the sole administration of exergame. Fifty-eight participants were randomly assigned to one of two groups (N = 29 each group) in a parallel, double-blind, randomized controlled trial lasting 26 weeks. The experimental group received daily fish oil, whereas the control group received daily olive oil. After 16 weeks, both groups started with an exergame training. Measurements were performed pre, during, and post intervention. Primary outcomes were recruitment curves using transcranial magnetic stimulation and response-locked potentials using electroencephalography. Secondary outcomes included executive functions and gait parameters. Blood samples were taken to control for FAs. Forty-three individuals (mean age 69.4 ± 4.6 years) completed the study (Nexperimental = 22, Ncontrol = 21). The results showed no significant time × group interaction effects for any parameters. Blood samples demonstrated significant time × group interaction effects. Post-hoc tests showed a significant increase of omega-3 FAs (p < .001) and a significant decrease of omega-6 FAs (p < .001) for the experimental group. The combination of exergame training and fish oil did not lead to additional beneficial effects. To trigger possible effects, future studies should carefully consider study design aspects; e.g. study duration, individual nutritional supplementation dose, omega-3 FAs supplementation composition, and placebo. Furthermore, studies should consider neuroimaging methods as these might be more sensitive to assess early brain adaptations. Thus, future studies should be aware of several aspects running a combinatory study that includes omega-3 FAs according to their expected effects. Swiss National Clinical Trials SNCTP000001623 and ISRCTN12084831 registered 30 November 2015." @default.
- W2938813031 created "2019-04-25" @default.
- W2938813031 creator A5001205095 @default.
- W2938813031 creator A5002902014 @default.
- W2938813031 creator A5051623464 @default.
- W2938813031 creator A5074579599 @default.
- W2938813031 creator A5079757686 @default.
- W2938813031 creator A5086204913 @default.
- W2938813031 date "2019-03-13" @default.
- W2938813031 modified "2023-09-30" @default.
- W2938813031 title "Effects of exergame training combined with omega-3 fatty acids on the elderly brain: a randomized double-blind placebo-controlled trial" @default.
- W2938813031 cites W1500922888 @default.
- W2938813031 cites W1526926544 @default.
- W2938813031 cites W1544359545 @default.
- W2938813031 cites W1594827615 @default.
- W2938813031 cites W1745521526 @default.
- W2938813031 cites W1847168837 @default.
- W2938813031 cites W1864551508 @default.
- W2938813031 cites W1963525603 @default.
- W2938813031 cites W1966821136 @default.
- W2938813031 cites W1967333153 @default.
- W2938813031 cites W1971091197 @default.
- W2938813031 cites W1971351343 @default.
- W2938813031 cites W1975893639 @default.
- W2938813031 cites W1978165201 @default.
- W2938813031 cites W1979899459 @default.
- W2938813031 cites W1981204020 @default.
- W2938813031 cites W1982662477 @default.
- W2938813031 cites W1982742157 @default.
- W2938813031 cites W1985023627 @default.
- W2938813031 cites W1989472717 @default.
- W2938813031 cites W1994947322 @default.
- W2938813031 cites W1995876047 @default.
- W2938813031 cites W2008813344 @default.
- W2938813031 cites W2008854521 @default.
- W2938813031 cites W2016250746 @default.
- W2938813031 cites W2017976379 @default.
- W2938813031 cites W2020031936 @default.
- W2938813031 cites W2025541693 @default.
- W2938813031 cites W2029313053 @default.
- W2938813031 cites W2032541700 @default.
- W2938813031 cites W2037399908 @default.
- W2938813031 cites W2044948389 @default.
- W2938813031 cites W2053884681 @default.
- W2938813031 cites W2055964704 @default.
- W2938813031 cites W2058161128 @default.
- W2938813031 cites W2062863623 @default.
- W2938813031 cites W2064623130 @default.
- W2938813031 cites W2067374489 @default.
- W2938813031 cites W2070558694 @default.
- W2938813031 cites W2072348905 @default.
- W2938813031 cites W2073982465 @default.
- W2938813031 cites W2074269574 @default.
- W2938813031 cites W2074786896 @default.
- W2938813031 cites W2081186689 @default.
- W2938813031 cites W2082591782 @default.
- W2938813031 cites W2085435800 @default.
- W2938813031 cites W2087468607 @default.
- W2938813031 cites W2089713526 @default.
- W2938813031 cites W2091163929 @default.
- W2938813031 cites W2094692905 @default.
- W2938813031 cites W2097799979 @default.
- W2938813031 cites W2098643673 @default.
- W2938813031 cites W2098825532 @default.
- W2938813031 cites W2098997562 @default.
- W2938813031 cites W2104285446 @default.
- W2938813031 cites W2108948907 @default.
- W2938813031 cites W2109140840 @default.
- W2938813031 cites W2112519660 @default.
- W2938813031 cites W2114565884 @default.
- W2938813031 cites W2117324855 @default.
- W2938813031 cites W2119754857 @default.
- W2938813031 cites W2120469313 @default.
- W2938813031 cites W2123163997 @default.
- W2938813031 cites W2128495200 @default.
- W2938813031 cites W2132312934 @default.
- W2938813031 cites W2133707965 @default.
- W2938813031 cites W2134120248 @default.
- W2938813031 cites W2136145120 @default.
- W2938813031 cites W2136906814 @default.
- W2938813031 cites W2137070227 @default.
- W2938813031 cites W2139657323 @default.
- W2938813031 cites W2140059276 @default.
- W2938813031 cites W2142997107 @default.
- W2938813031 cites W2143617418 @default.
- W2938813031 cites W2144165392 @default.
- W2938813031 cites W2144181853 @default.
- W2938813031 cites W2145555293 @default.
- W2938813031 cites W2148080316 @default.
- W2938813031 cites W2154321205 @default.
- W2938813031 cites W2157371835 @default.
- W2938813031 cites W2167241906 @default.
- W2938813031 cites W2167311298 @default.
- W2938813031 cites W2169496098 @default.
- W2938813031 cites W2206521839 @default.
- W2938813031 cites W2315929518 @default.
- W2938813031 cites W2331630337 @default.
- W2938813031 cites W2396499118 @default.
- W2938813031 cites W2418340212 @default.
- W2938813031 cites W2472705739 @default.