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- W2938863656 abstract "In this narrative review, we discuss use of second-generation antipsychotics (SGAs) in maintenance treatment of bipolar disorder. We compare their use to historically more established treatments (particularly lithium, the gold standard). To compare we review evidence on efficacy, effectiveness and tolerability across illness poles, possible mechanisms of treatment response, guidance given by guideline groups and pragmatic clinical considerations. We then illustrate the controversies in maintenance antipsychotic use, with the example of first episode mania and its treatment within first episode psychosis services. Finally, we make suggestions for future studies to unpick these differences." @default.
- W2938863656 created "2019-04-25" @default.
- W2938863656 creator A5017057708 @default.
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- W2938863656 date "2019-03-27" @default.
- W2938863656 modified "2023-10-16" @default.
- W2938863656 title "Controversies in bipolar disorder; role of second-generation antipsychotic for maintenance therapy" @default.
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- W2938863656 doi "https://doi.org/10.1186/s40345-019-0145-0" @default.
- W2938863656 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6435763" @default.
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