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• W2938897492 abstract "Feminizing hormone therapy (FHT) may interact with human immunodeficiency virus preexposure prophylaxis (PrEP). We found that transgender women who took FHT exhibited a 7-fold lower rectal tissue ratio of PrEP's active metabolites vs competing deoxynucleotides compared to cisgender women and men (P = .03) that inversely correlated with estradiol (ρ = -0.79; P < .05). Thus, FHT may negatively impact PrEP efficacy. Clinical Trials Registration . NCT02983110." @default.
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• W2938897492 date "2019-04-09" @default.
• W2938897492 modified "2023-10-17" @default.
• W2938897492 title "Decreased Tenofovir Diphosphate Concentrations in a Transgender Female Cohort: Implications for Human Immunodeficiency Virus Preexposure Prophylaxis" @default.
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• W2938897492 doi "https://doi.org/10.1093/cid/ciz290" @default.
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