Matches in SemOpenAlex for { <https://semopenalex.org/work/W2938961215> ?p ?o ?g. }
- W2938961215 abstract "The population genetics of most range expansions is thought to be shaped by the competition between Darwinian selection and random genetic drift at the range margins. Here, we show that the evolutionary dynamics during range expansions is highly sensitive to additional fluctuations induced by environmental heterogeneities. Tracking mutant clones with a tunable fitness effect in bacterial colonies grown on randomly patterned surfaces we found that environmental heterogeneity can dramatically reduce the efficacy of selection. Time-lapse microscopy and computer simulations suggest that this effect arises generically from a local 'pinning' of the expansion front, whereby stretches of the front are slowed down on a length scale that depends on the structure of the environmental heterogeneity. This pinning focuses the range expansion into a small number of 'lucky' individuals with access to expansion paths, altering the neutral evolutionary dynamics and increasing the importance of chance relative to selection." @default.
- W2938961215 created "2019-04-25" @default.
- W2938961215 creator A5038587254 @default.
- W2938961215 creator A5039329500 @default.
- W2938961215 date "2019-04-12" @default.
- W2938961215 modified "2023-10-16" @default.
- W2938961215 title "Environmental heterogeneity can tip the population genetics of range expansions" @default.
- W2938961215 cites W1872853220 @default.
- W2938961215 cites W1965050160 @default.
- W2938961215 cites W1973780630 @default.
- W2938961215 cites W1980331265 @default.
- W2938961215 cites W1982886317 @default.
- W2938961215 cites W1991037583 @default.
- W2938961215 cites W1993153669 @default.
- W2938961215 cites W1995566547 @default.
- W2938961215 cites W1997722194 @default.
- W2938961215 cites W2000492287 @default.
- W2938961215 cites W2001605178 @default.
- W2938961215 cites W2002237201 @default.
- W2938961215 cites W2003029750 @default.
- W2938961215 cites W2005545097 @default.
- W2938961215 cites W2009644537 @default.
- W2938961215 cites W2012294035 @default.
- W2938961215 cites W2020281792 @default.
- W2938961215 cites W2036279792 @default.
- W2938961215 cites W2044313416 @default.
- W2938961215 cites W2048139926 @default.
- W2938961215 cites W2051334294 @default.
- W2938961215 cites W2059905849 @default.
- W2938961215 cites W2068559979 @default.
- W2938961215 cites W2068679831 @default.
- W2938961215 cites W2079949023 @default.
- W2938961215 cites W2087496472 @default.
- W2938961215 cites W2088046890 @default.
- W2938961215 cites W2094778706 @default.
- W2938961215 cites W2106179897 @default.
- W2938961215 cites W2106629677 @default.
- W2938961215 cites W2112357013 @default.
- W2938961215 cites W2116120826 @default.
- W2938961215 cites W2118400404 @default.
- W2938961215 cites W2129008567 @default.
- W2938961215 cites W2149354969 @default.
- W2938961215 cites W2149903267 @default.
- W2938961215 cites W2157874555 @default.
- W2938961215 cites W2160803964 @default.
- W2938961215 cites W2161950775 @default.
- W2938961215 cites W2257432813 @default.
- W2938961215 cites W2416195381 @default.
- W2938961215 cites W2487150154 @default.
- W2938961215 cites W2511099695 @default.
- W2938961215 cites W2529657394 @default.
- W2938961215 cites W2556682019 @default.
- W2938961215 cites W2557739189 @default.
- W2938961215 cites W2571828103 @default.
- W2938961215 cites W2572203408 @default.
- W2938961215 cites W2799944639 @default.
- W2938961215 cites W2807643095 @default.
- W2938961215 cites W2888856942 @default.
- W2938961215 cites W2901437229 @default.
- W2938961215 cites W2921290863 @default.
- W2938961215 cites W2938961215 @default.
- W2938961215 cites W2950797136 @default.
- W2938961215 cites W2950802561 @default.
- W2938961215 cites W2952255265 @default.
- W2938961215 cites W2952985348 @default.
- W2938961215 cites W2953145711 @default.
- W2938961215 cites W2962702983 @default.
- W2938961215 cites W2977474616 @default.
- W2938961215 cites W3101133580 @default.
- W2938961215 cites W3101137429 @default.
- W2938961215 cites W3103765359 @default.
- W2938961215 cites W3106263639 @default.
- W2938961215 cites W4236605885 @default.
- W2938961215 cites W4240077652 @default.
- W2938961215 cites W4312277008 @default.
- W2938961215 doi "https://doi.org/10.7554/elife.44359" @default.
- W2938961215 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6513619" @default.
- W2938961215 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30977724" @default.
- W2938961215 hasPublicationYear "2019" @default.
- W2938961215 type Work @default.
- W2938961215 sameAs 2938961215 @default.
- W2938961215 citedByCount "42" @default.
- W2938961215 countsByYear W29389612152019 @default.
- W2938961215 countsByYear W29389612152020 @default.
- W2938961215 countsByYear W29389612152021 @default.
- W2938961215 countsByYear W29389612152022 @default.
- W2938961215 countsByYear W29389612152023 @default.
- W2938961215 crossrefType "journal-article" @default.
- W2938961215 hasAuthorship W2938961215A5038587254 @default.
- W2938961215 hasAuthorship W2938961215A5039329500 @default.
- W2938961215 hasBestOaLocation W29389612151 @default.
- W2938961215 hasConcept C104317684 @default.
- W2938961215 hasConcept C144024400 @default.
- W2938961215 hasConcept C149923435 @default.
- W2938961215 hasConcept C154945302 @default.
- W2938961215 hasConcept C1570309 @default.
- W2938961215 hasConcept C159985019 @default.
- W2938961215 hasConcept C171578705 @default.
- W2938961215 hasConcept C18903297 @default.
- W2938961215 hasConcept C192562407 @default.