FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2939208928> ?p ?o ?g. }

• W2939208928 endingPage "451" @default.
• W2939208928 startingPage "445" @default.
• W2939208928 abstract "The purpose of the study was to determine oxidative stress-related plasma thiol/disulphide, ischemia-modified albumin (IMA) levels and ferroxidase activity among women with obesity in insulin-resistant and non-insulin-resistant groups in comparison with an overweight group.We compared plasma thiol/disulphide, IMA levels, and ferroxidase activity between the study groups. We analyzed plasma thiol/disulphide homeostasis with a newly developed automated measurement method; IMA with Albumin Cobalt Binding Test and ferroxidase (ceruloplasmin) levels with an automated, colourimetric method.There were no significant differences between insulin-resistant and non-insulin-resistant women with obesity in terms of plasma native thiol, total thiol, disulphide, disulphide/native thiol ratio, disulphide/total thiol or native thiol/total thiol values. Ferroxidase activity was higher in insulin-resistant than in non-insulin-resistant women with obesity and higher in the total women with obesity group than in the overweight subjects (p<0.001, and p=0.014, respectively). IMA was lower in the insulin-resistant group than in the non-insulin-resistant group and overweight groups (p=0.011, and p=0.042, respectively).The significantly greater increase in ferroxidase activity in insulin-resistant subjects with obesity may reflect its role as a positive acute phase protein. These findings may be related to the pathogenesis of the disease. Changes in oxidative status occur in women with obesity, and partially in overweight subjects. The ferroxidase activity of ceruloplasmin plays a crucial role in iron homeostasis and lowers oxidative stress by reducing the detrimental effects of iron.Svrha ove studije bila je da se odredi nivo oksidativnog stresa vezan za plazma tiol/disulfid, nivo ishemijski modifikovanog albumina (IMA) i aktivnost fer oksidaze kod gojaznih žena iz insulinski rezistentne i nerezistentne grupe u poređenju sa grupom žena sa prekomernom težinom.Uporedili smo plazma tiol/disulfid, nivoe IMA i aktivnost feroksidaze među ispitivanim grupama. Analizirali smo plazma tiol/disulfidnu homeostazu pomoću novorazvijene automatizovane metode merenja, IMA testom vezivanja albumin kobalta, a feroksidazu (ceruloplazmin) automatizovanom kolorimetrijskom metodom.Nije bilo značajnih razlika između insulinski rezistentnih i nerezistentnih žena i gojaznih žena u smislu vrednosti koje se odnose na prirodni tiol, ukupni tiol, disulfid, odnos disulfid/prirodni tiol, disulfid/ukupni tiol ili prirodni tiol/ukupni tiol. Aktivnost feroksidaze bila je viša kod žena rezistentnih na insulin nego kod gojaznih žena koje nisu insulinski rezistentne, a veća je u ukupnom broju gojaznih nego kod ispitanica sa prekomernom težinom (p < 0,001 i p = 0,014, po ispitivanju). IMA je bio niži u grupi koja je rezistentna na insulin nego u grupama koje nisu rezistentne na insulin i grupi sa prekomernom težinom (p = 0,011 i p = 0,042).Značajno veće povećanje aktivnosti feroksidaze kod gojaznih subjekata otpornih na insulin može odražavati njegovu ulogu kao pozitivnog proteina akutne faze. Ovi nalazi mogu biti povezani sa patogenezom bolesti. Promene u oksidativnom statusu javljaju se kod gojaznih žena i delimično kod ispitanica sa prekomernom težinom. Feroksidazna aktivnost ceruloplazmina igra ključnu ulogu u homeostazi gvožđa i smanjuje oksidativni stres smanjenjem štetnih efekata gvožđa." @default.
• W2939208928 created "2019-04-25" @default.
• W2939208928 creator A5012778283 @default.
• W2939208928 creator A5014971724 @default.
• W2939208928 creator A5016655845 @default.
• W2939208928 creator A5035759365 @default.
• W2939208928 creator A5071981009 @default.
• W2939208928 date "2019-03-26" @default.
• W2939208928 modified "2023-09-25" @default.
• W2939208928 title "Thiol/Disulphide homeostasis, ischemia modified albumin, and ferroxidase as oxidative stress markers in women with obesity with insulin resistance" @default.
• W2939208928 cites W1538929849 @default.
• W2939208928 cites W1971291382 @default.
• W2939208928 cites W1996620824 @default.
• W2939208928 cites W2003480609 @default.
• W2939208928 cites W2051639904 @default.
• W2939208928 cites W2051643227 @default.
• W2939208928 cites W2054306914 @default.
• W2939208928 cites W2061962106 @default.
• W2939208928 cites W2087576630 @default.
• W2939208928 cites W2096427004 @default.
• W2939208928 cites W2120563796 @default.
• W2939208928 cites W2123766313 @default.
• W2939208928 cites W2155704907 @default.
• W2939208928 cites W2164208660 @default.
• W2939208928 cites W2195190426 @default.
• W2939208928 cites W2305438786 @default.
• W2939208928 cites W2339163277 @default.
• W2939208928 cites W2398178889 @default.
• W2939208928 cites W2400729024 @default.
• W2939208928 cites W2519873703 @default.
• W2939208928 cites W2541779647 @default.
• W2939208928 cites W2553149284 @default.
• W2939208928 cites W2561691077 @default.
• W2939208928 cites W2737694388 @default.
• W2939208928 cites W2795070146 @default.
• W2939208928 cites W2801390563 @default.
• W2939208928 cites W2901652829 @default.
• W2939208928 doi "https://doi.org/10.2478/jomb-2019-0015" @default.
• W2939208928 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6708298" @default.
• W2939208928 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31496908" @default.
• W2939208928 hasPublicationYear "2019" @default.
• W2939208928 type Work @default.
• W2939208928 sameAs 2939208928 @default.
• W2939208928 citedByCount "16" @default.
• W2939208928 countsByYear W29392089282019 @default.
• W2939208928 countsByYear W29392089282020 @default.
• W2939208928 countsByYear W29392089282021 @default.
• W2939208928 countsByYear W29392089282022 @default.
• W2939208928 countsByYear W29392089282023 @default.
• W2939208928 crossrefType "journal-article" @default.
• W2939208928 hasAuthorship W2939208928A5012778283 @default.
• W2939208928 hasAuthorship W2939208928A5014971724 @default.
• W2939208928 hasAuthorship W2939208928A5016655845 @default.
• W2939208928 hasAuthorship W2939208928A5035759365 @default.
• W2939208928 hasAuthorship W2939208928A5071981009 @default.
• W2939208928 hasBestOaLocation W29392089281 @default.
• W2939208928 hasConcept C126322002 @default.
• W2939208928 hasConcept C134018914 @default.
• W2939208928 hasConcept C185592680 @default.
• W2939208928 hasConcept C2776125364 @default.
• W2939208928 hasConcept C2776151105 @default.
• W2939208928 hasConcept C2777391703 @default.
• W2939208928 hasConcept C2779306644 @default.
• W2939208928 hasConcept C2780586474 @default.
• W2939208928 hasConcept C2781324293 @default.
• W2939208928 hasConcept C28452662 @default.
• W2939208928 hasConcept C511355011 @default.
• W2939208928 hasConcept C55493867 @default.
• W2939208928 hasConcept C63645605 @default.
• W2939208928 hasConcept C71924100 @default.
• W2939208928 hasConceptScore W2939208928C126322002 @default.
• W2939208928 hasConceptScore W2939208928C134018914 @default.
• W2939208928 hasConceptScore W2939208928C185592680 @default.
• W2939208928 hasConceptScore W2939208928C2776125364 @default.
• W2939208928 hasConceptScore W2939208928C2776151105 @default.
• W2939208928 hasConceptScore W2939208928C2777391703 @default.
• W2939208928 hasConceptScore W2939208928C2779306644 @default.
• W2939208928 hasConceptScore W2939208928C2780586474 @default.
• W2939208928 hasConceptScore W2939208928C2781324293 @default.
• W2939208928 hasConceptScore W2939208928C28452662 @default.
• W2939208928 hasConceptScore W2939208928C511355011 @default.
• W2939208928 hasConceptScore W2939208928C55493867 @default.
• W2939208928 hasConceptScore W2939208928C63645605 @default.
• W2939208928 hasConceptScore W2939208928C71924100 @default.
• W2939208928 hasIssue "4" @default.
• W2939208928 hasLocation W29392089281 @default.
• W2939208928 hasLocation W29392089282 @default.
• W2939208928 hasLocation W29392089283 @default.
• W2939208928 hasLocation W29392089284 @default.
• W2939208928 hasOpenAccess W2939208928 @default.
• W2939208928 hasPrimaryLocation W29392089281 @default.
• W2939208928 hasRelatedWork W138803513 @default.
• W2939208928 hasRelatedWork W1979252938 @default.
• W2939208928 hasRelatedWork W1983641721 @default.
• W2939208928 hasRelatedWork W1986132654 @default.
• W2939208928 hasRelatedWork W2010140898 @default.
• W2939208928 hasRelatedWork W2074673535 @default.
• W2939208928 hasRelatedWork W2082140668 @default.

• next