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• W2939232228 abstract "This study investigated the most important epidemiological characteristics of C. perfringens strains colonizing the intestine of Jordanian infants.A total of 302 fecal samples were collected from Jordanian infants aged ≤ 1 year from patients hospitalized in the neonatal intensive care unit and from the outpatient department. Samples were cultured for detection of C. perfringens and evaluation of their antimicrobial resistance; identification of their potential toxins genes was performed using PCR.Overall the C. perfringens colonization rate was 27.2% (82/302). Infants aged ≤ 6 months showed significantly higher (p<0.004) colonization than older infants. The occurrence rates of C. perfringens isolates carrying potential specific toxin genes were as follows: alpha toxin 95.1% (78/82), beta-2 toxin 69.5% (57/82), beta toxin 14.6% (12/82), and only 2.4% (2/82) epsilon toxin. No isolate carried the iota toxin. Genotype A was the most prevalent among C. perfringens isolates (78.1%). The antimicrobial resistance rates of C. perfringens isolates were 20% to metronidazole and erythromycin, 16.7% to levofloxacin, and 6.7% to vancomycin.This study demonstrates that the majority of C. perfringens isolates from feces of Jordanian infants were classified as type A, few isolates were classified as type C and type D, and all were negative for potential enterotoxin genes causing diarrhea." @default.
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• W2939232228 date "2019-03-01" @default.
• W2939232228 modified "2023-09-26" @default.
• W2939232228 title "Diversity of toxin genotypes and antimicrobial susceptibility of Clostridium perfringens isolates from feces of infants" @default.
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• W2939232228 doi "https://doi.org/10.18683/germs.2019.1154" @default.
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