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- W2939363468 abstract "Background: In a multitude of retrospective studies, the impact of tumor-associated mast cells on cancer outcome has been examined. However, so far present observational and experimental knowledge did not lead to successful translational approaches to the clinic. Herein we provide a systematic and comprehensive analysis of mast cell biology across human cancer entities, assessing their spatial cell distribution and revealing that mast cell presence in tumors, with a high tropism to adipose-rich areas, correlates to an inflamed phenotype in ovarian cancer, but enables selective targeting for cancer immunotherapy." @default.
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- W2939363468 date "2019-03-01" @default.
- W2939363468 modified "2023-09-27" @default.
- W2939363468 title "Cancer associated mast cells exhibit a tumor promoting phenotype but can be effectively targeted to reinvigorate antitumor immunity in a human based ex-vivo model" @default.
- W2939363468 doi "https://doi.org/10.1016/j.ejca.2019.01.050" @default.
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