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• W2939505877 abstract "Pancreatic cancer (PC) remains a disease characterized by an extremely poor prognosis, which is often limited by advanced tumor stage at diagnosis. As surgery remains the only option for long-term survival, indications for resection to achieve a complete tumor removal have been extended in recent years, including locally advanced as well as metastatic disease. Here, we provide a literature overview of modern multimodal treatment concepts of metastatic PC focused on surgery and local interventions including neoadjuvant concepts, stratification of patients, prognostic parameters, and oncological outcomes. The current literature lacks level I evidence studies on surgery in stage IV PC. The available observational studies show that resection for liver metastasis has been increasingly performed in recent years, outcomes improve after neoadjuvant therapy, and certain prognostic parameters can identify patients who benefit from this approach. In addition, interventional or radio-oncological liver-directed therapies have been evaluated showing the possibility of some disease control. Resection of pulmonary metastases is rarely performed, although this patient subgroup may have a more favorable prognosis than patients with stage IV liver cancer. Surgery in the setting of peritoneal carcinomatosis remains experimental without any valid supporting data. There are promising data to support resection of metastatic PC, presuming this approach is embedded in a multimodal oncological concept with modern and effective multi-agent chemotherapies and proper patient selection. Based on this, future studies should specify distinct groups of patients who benefit from extended surgical approaches including synchronous or staged metastasectomy." @default.
• W2939505877 created "2019-04-25" @default.
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• W2939505877 creator A5088835174 @default.
• W2939505877 date "2019-04-15" @default.
• W2939505877 modified "2023-10-18" @default.
• W2939505877 title "Surgical and local therapeutic concepts of oligometastatic pancreatic cancer in the era of effective chemotherapy" @default.
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• W2939505877 cites W1970415573 @default.
• W2939505877 cites W1974922522 @default.
• W2939505877 cites W1977924585 @default.
• W2939505877 cites W2005858161 @default.
• W2939505877 cites W2012683680 @default.
• W2939505877 cites W2021228878 @default.
• W2939505877 cites W2027442674 @default.
• W2939505877 cites W2037648483 @default.
• W2939505877 cites W2044019893 @default.
• W2939505877 cites W2052706552 @default.
• W2939505877 cites W2059328393 @default.
• W2939505877 cites W2064813713 @default.
• W2939505877 cites W2090749716 @default.
• W2939505877 cites W2092258249 @default.
• W2939505877 cites W2093882511 @default.
• W2939505877 cites W2107780185 @default.
• W2939505877 cites W2113501719 @default.
• W2939505877 cites W2113566724 @default.
• W2939505877 cites W2121490159 @default.
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• W2939505877 cites W2312965253 @default.
• W2939505877 cites W2326967233 @default.
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• W2939505877 cites W2572552863 @default.
• W2939505877 cites W2575139177 @default.
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• W2939505877 cites W2891199630 @default.
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• W2939505877 cites W2899798400 @default.
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• W2939505877 doi "https://doi.org/10.1007/s10353-019-0589-6" @default.
• W2939505877 hasPublicationYear "2019" @default.
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