FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2939630857> ?p ?o ?g. }

• W2939630857 endingPage "1168" @default.
• W2939630857 startingPage "1168" @default.
• W2939630857 abstract "Background and purpose The efficacy of dual antiplatelet treatment may be modified by many factors. The aim was to assess whether the effect of clopidogrel plus aspirin versus aspirin alone on recurrent stroke would be affected by admission activated partial thromboplastin time ( aPTT ). Methods Data were derived from the Clopidogrel in High‐Risk Patients with Acute Nondisabling Cerebrovascular Events ( CHANCE ) trial. A total of 5074 patients were categorized into three groups based on the aPTT distribution according to the 15th and 85th percentile. The primary outcome was any stroke within 90 days. The interaction of aPTT with antiplatelet therapy on stroke risk was assessed with a Cox proportional hazards model with adjustment for covariates. Results In the high aPTT group (defined as ≥35.9 s), stroke occurred in 6.7% of patients in the clopidogrel–aspirin arm and 11.9% in the aspirin arm [adjusted hazard ratio ( HR ) 0.50; 95% confidence interval ( CI ) 0.29–0.85]. In the medium aPTT group (24.6–35.8 s), stroke occurred in 7.7% of patients in the clopidogrel–aspirin arm and 11.8% in the aspirin arm (adjusted HR 0.62; 95% CI 0.50–0.75). Furthermore, in the low aPTT group (≤24.5 s), stroke occurred in 11.2% of patients in the clopidogrel–aspirin arm and 9.9% in the aspirin arm (adjusted HR 1.07; 95% CI 0.65–1.62). The interaction P value of antiplatelet therapy with aPTT level at the cut‐point of approximately 25 s or below was significant ( P < 0.05). Conclusions Dual antiplatelet therapy was superior to single antiplatelet therapy in the high or medium aPTT group but not in the low aPTT group." @default.
• W2939630857 created "2019-04-25" @default.
• W2939630857 creator A5005568994 @default.
• W2939630857 creator A5036644714 @default.
• W2939630857 creator A5046038877 @default.
• W2939630857 creator A5046732096 @default.
• W2939630857 creator A5068495173 @default.
• W2939630857 creator A5070324288 @default.
• W2939630857 creator A5071087510 @default.
• W2939630857 creator A5075764283 @default.
• W2939630857 creator A5085604291 @default.
• W2939630857 date "2019-05-09" @default.
• W2939630857 modified "2023-10-16" @default.
• W2939630857 title "Effect of dual versus mono antiplatelet therapy on recurrent stroke modulated by activated partial thromboplastin time" @default.
• W2939630857 cites W1981877600 @default.
• W2939630857 cites W200264917 @default.
• W2939630857 cites W2004055935 @default.
• W2939630857 cites W2034415641 @default.
• W2939630857 cites W2046011250 @default.
• W2939630857 cites W2048611276 @default.
• W2939630857 cites W2063532159 @default.
• W2939630857 cites W2071343574 @default.
• W2939630857 cites W2081615170 @default.
• W2939630857 cites W2091112630 @default.
• W2939630857 cites W2124894748 @default.
• W2939630857 cites W2141646953 @default.
• W2939630857 cites W2162292125 @default.
• W2939630857 cites W2168719124 @default.
• W2939630857 cites W2361921955 @default.
• W2939630857 cites W2399388987 @default.
• W2939630857 cites W2489906651 @default.
• W2939630857 cites W2791615617 @default.
• W2939630857 cites W2804570339 @default.
• W2939630857 cites W2917123590 @default.
• W2939630857 doi "https://doi.org/10.1111/ene.13961" @default.
• W2939630857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30972875" @default.
• W2939630857 hasPublicationYear "2019" @default.
• W2939630857 type Work @default.
• W2939630857 sameAs 2939630857 @default.
• W2939630857 citedByCount "5" @default.
• W2939630857 countsByYear W29396308572020 @default.
• W2939630857 countsByYear W29396308572021 @default.
• W2939630857 countsByYear W29396308572022 @default.
• W2939630857 countsByYear W29396308572023 @default.
• W2939630857 crossrefType "journal-article" @default.
• W2939630857 hasAuthorship W2939630857A5005568994 @default.
• W2939630857 hasAuthorship W2939630857A5036644714 @default.
• W2939630857 hasAuthorship W2939630857A5046038877 @default.
• W2939630857 hasAuthorship W2939630857A5046732096 @default.
• W2939630857 hasAuthorship W2939630857A5068495173 @default.
• W2939630857 hasAuthorship W2939630857A5070324288 @default.
• W2939630857 hasAuthorship W2939630857A5071087510 @default.
• W2939630857 hasAuthorship W2939630857A5075764283 @default.
• W2939630857 hasAuthorship W2939630857A5085604291 @default.
• W2939630857 hasConcept C126322002 @default.
• W2939630857 hasConcept C127413603 @default.
• W2939630857 hasConcept C207103383 @default.
• W2939630857 hasConcept C2777628954 @default.
• W2939630857 hasConcept C2777849778 @default.
• W2939630857 hasConcept C2778261982 @default.
• W2939630857 hasConcept C2778382381 @default.
• W2939630857 hasConcept C2780645631 @default.
• W2939630857 hasConcept C42219234 @default.
• W2939630857 hasConcept C44249647 @default.
• W2939630857 hasConcept C71924100 @default.
• W2939630857 hasConcept C78519656 @default.
• W2939630857 hasConceptScore W2939630857C126322002 @default.
• W2939630857 hasConceptScore W2939630857C127413603 @default.
• W2939630857 hasConceptScore W2939630857C207103383 @default.
• W2939630857 hasConceptScore W2939630857C2777628954 @default.
• W2939630857 hasConceptScore W2939630857C2777849778 @default.
• W2939630857 hasConceptScore W2939630857C2778261982 @default.
• W2939630857 hasConceptScore W2939630857C2778382381 @default.
• W2939630857 hasConceptScore W2939630857C2780645631 @default.
• W2939630857 hasConceptScore W2939630857C42219234 @default.
• W2939630857 hasConceptScore W2939630857C44249647 @default.
• W2939630857 hasConceptScore W2939630857C71924100 @default.
• W2939630857 hasConceptScore W2939630857C78519656 @default.
• W2939630857 hasFunder F4320321540 @default.
• W2939630857 hasIssue "9" @default.
• W2939630857 hasLocation W29396308571 @default.
• W2939630857 hasLocation W29396308572 @default.
• W2939630857 hasOpenAccess W2939630857 @default.
• W2939630857 hasPrimaryLocation W29396308571 @default.
• W2939630857 hasRelatedWork W1584895772 @default.
• W2939630857 hasRelatedWork W2074593749 @default.
• W2939630857 hasRelatedWork W2096582894 @default.
• W2939630857 hasRelatedWork W2098366884 @default.
• W2939630857 hasRelatedWork W2133147248 @default.
• W2939630857 hasRelatedWork W2322221171 @default.
• W2939630857 hasRelatedWork W2351377190 @default.
• W2939630857 hasRelatedWork W2894283440 @default.
• W2939630857 hasRelatedWork W3043492355 @default.
• W2939630857 hasRelatedWork W95487621 @default.
• W2939630857 hasVolume "26" @default.
• W2939630857 isParatext "false" @default.
• W2939630857 isRetracted "false" @default.
• W2939630857 magId "2939630857" @default.

• next