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- W2939804946 abstract "Quality by Design (QbD) is a systematic, risk-based approach to pharmaceutical product and manufacturing development, which uses quality-improving scientific methods upstream in the research, development, and design phases, in order to assure that quality and safety are designed into product at as early stage as possible. This work focuses on the state-of-the-art applications of the QbD principles in the development of liposomes. The QbD approach has recently been proposed as a useful tool to obtain higher-quality liposomal products, as their development is a challenging task, involving intricate formulation and manufacturing processes. Thus, the current strategies to define the relationship between the critical material attributes or process parameters and product critical quality attributes and to establish the design space are overviewed. Additionally, the current characterization methodologies are described, as part of the control strategy required within the QbD paradigm." @default.
- W2939804946 created "2019-04-25" @default.
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- W2939804946 date "2019-09-04" @default.
- W2939804946 modified "2023-10-17" @default.
- W2939804946 title "Pharmaceutical Development of Liposomes Using the QbD Approach" @default.
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- W2939804946 doi "https://doi.org/10.5772/intechopen.85374" @default.
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