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- W2940249737 endingPage "584" @default.
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- W2940249737 abstract "Abstract Pulmonary and systemic insults from inhalation injury can complicate the care of burn patients and contribute to significant morbidity and mortality. However, recent progress in diagnosis and treatment of inhalation injury has not kept pace with the care of cutaneous thermal injury. There are many challenges unique to inhalation injury that have slowed advancement, including deficiencies in our understanding of its pathophysiology, the relative difficulty and subjectivity of bronchoscopic diagnosis, the lack of diagnostic biomarkers, the necessarily urgent manner in which decisions are made about intubation, and the lack of universal recommendations for the application of mucolytics, anticoagulants, bronchodilators, modified ventilator strategies, and other measures. This review represents a summary of critical shortcomings in our understanding and management of inhalation injury identified by the American Burn Association’s working group on Cutaneous Thermal Injury and Inhalation Injury in 2018. It addresses our current understanding of the diagnosis, pathophysiology, and treatment of inhalation injury and highlights topics in need of additional research, including 1) airway repair mechanisms; 2) the airway microbiome in health and after injury; and 3) candidate biomarkers of inhalation injury." @default.
- W2940249737 created "2019-04-25" @default.
- W2940249737 creator A5030596322 @default.
- W2940249737 creator A5034398180 @default.
- W2940249737 creator A5036347283 @default.
- W2940249737 creator A5054710887 @default.
- W2940249737 creator A5057884966 @default.
- W2940249737 creator A5084027124 @default.
- W2940249737 date "2019-04-11" @default.
- W2940249737 modified "2023-09-26" @default.
- W2940249737 title "Inhalation Injury: Unmet Clinical Needs and Future Research" @default.
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