Matches in SemOpenAlex for { <https://semopenalex.org/work/W2940455811> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2940455811 endingPage "1783" @default.
- W2940455811 startingPage "1776" @default.
- W2940455811 abstract "Abstract Background The microspheres are one of the major formulations in the novel drug delivery systems. These days' scientists are predominantly focusing on natural plant products because of the poisonous effect of synthetic drug molecules. From olden days itself, neem has some excellent antibacterial activities. Aims The main objective of the research work was to formulate microspheres containing methanolic extract of neem and incorporate it into a gel. The optimized gel was evaluated for its antibacterial activity. Methods The methanolic extract of the neem leaves was prepared by maceration process. The microspheres prepared were evaluated for shape, size of particles, and in vitro drug release. Out of all the formulations, the F5 formulation was found to be optimized; therefore, it was incorporated into the gel and evaluated for the in vitro permeation studies, in vivo skin irritation test, in vitro antibacterial activity studies, and accelerated stability studies. Results The prepared gel formulation showed an acceptable zone of inhibition when compared to the pure drug in in vitro antibacterial activity studies. The skin irritation study on albino Wistar rats showed that the prepared gel formulation was compatible. Based on the stability studies, the gel formulation was found to be stable during the study period. Conclusion The optimized formulation of containing neem extract showed better antibacterial activity, and it could be promising one in the topical delivery of neem for treatment of bacterial infections." @default.
- W2940455811 created "2019-05-03" @default.
- W2940455811 creator A5022776660 @default.
- W2940455811 creator A5070281056 @default.
- W2940455811 date "2019-04-23" @default.
- W2940455811 modified "2023-10-16" @default.
- W2940455811 title "Development and evaluation of novel topical gel of neem extract for the treatment of bacterial infections" @default.
- W2940455811 cites W1976656293 @default.
- W2940455811 cites W1989373679 @default.
- W2940455811 cites W1993144465 @default.
- W2940455811 cites W2014770633 @default.
- W2940455811 cites W2036406749 @default.
- W2940455811 cites W2060370203 @default.
- W2940455811 cites W2061456507 @default.
- W2940455811 cites W2074763349 @default.
- W2940455811 cites W2091211077 @default.
- W2940455811 cites W2165706982 @default.
- W2940455811 cites W2772622543 @default.
- W2940455811 cites W2883025521 @default.
- W2940455811 cites W2889344339 @default.
- W2940455811 doi "https://doi.org/10.1111/jocd.12965" @default.
- W2940455811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31012982" @default.
- W2940455811 hasPublicationYear "2019" @default.
- W2940455811 type Work @default.
- W2940455811 sameAs 2940455811 @default.
- W2940455811 citedByCount "8" @default.
- W2940455811 countsByYear W29404558112021 @default.
- W2940455811 countsByYear W29404558112022 @default.
- W2940455811 countsByYear W29404558112023 @default.
- W2940455811 crossrefType "journal-article" @default.
- W2940455811 hasAuthorship W2940455811A5022776660 @default.
- W2940455811 hasAuthorship W2940455811A5070281056 @default.
- W2940455811 hasConcept C150903083 @default.
- W2940455811 hasConcept C159985019 @default.
- W2940455811 hasConcept C16005928 @default.
- W2940455811 hasConcept C185592680 @default.
- W2940455811 hasConcept C192562407 @default.
- W2940455811 hasConcept C202751555 @default.
- W2940455811 hasConcept C203014093 @default.
- W2940455811 hasConcept C207001950 @default.
- W2940455811 hasConcept C2777063393 @default.
- W2940455811 hasConcept C2780104969 @default.
- W2940455811 hasConcept C3019129585 @default.
- W2940455811 hasConcept C43617362 @default.
- W2940455811 hasConcept C523546767 @default.
- W2940455811 hasConcept C54355233 @default.
- W2940455811 hasConcept C55493867 @default.
- W2940455811 hasConcept C556039675 @default.
- W2940455811 hasConcept C71924100 @default.
- W2940455811 hasConcept C74940592 @default.
- W2940455811 hasConcept C86803240 @default.
- W2940455811 hasConcept C98274493 @default.
- W2940455811 hasConceptScore W2940455811C150903083 @default.
- W2940455811 hasConceptScore W2940455811C159985019 @default.
- W2940455811 hasConceptScore W2940455811C16005928 @default.
- W2940455811 hasConceptScore W2940455811C185592680 @default.
- W2940455811 hasConceptScore W2940455811C192562407 @default.
- W2940455811 hasConceptScore W2940455811C202751555 @default.
- W2940455811 hasConceptScore W2940455811C203014093 @default.
- W2940455811 hasConceptScore W2940455811C207001950 @default.
- W2940455811 hasConceptScore W2940455811C2777063393 @default.
- W2940455811 hasConceptScore W2940455811C2780104969 @default.
- W2940455811 hasConceptScore W2940455811C3019129585 @default.
- W2940455811 hasConceptScore W2940455811C43617362 @default.
- W2940455811 hasConceptScore W2940455811C523546767 @default.
- W2940455811 hasConceptScore W2940455811C54355233 @default.
- W2940455811 hasConceptScore W2940455811C55493867 @default.
- W2940455811 hasConceptScore W2940455811C556039675 @default.
- W2940455811 hasConceptScore W2940455811C71924100 @default.
- W2940455811 hasConceptScore W2940455811C74940592 @default.
- W2940455811 hasConceptScore W2940455811C86803240 @default.
- W2940455811 hasConceptScore W2940455811C98274493 @default.
- W2940455811 hasIssue "6" @default.
- W2940455811 hasLocation W29404558111 @default.
- W2940455811 hasLocation W29404558112 @default.
- W2940455811 hasOpenAccess W2940455811 @default.
- W2940455811 hasPrimaryLocation W29404558111 @default.
- W2940455811 hasRelatedWork W2008385972 @default.
- W2940455811 hasRelatedWork W2183204011 @default.
- W2940455811 hasRelatedWork W2187371766 @default.
- W2940455811 hasRelatedWork W2359625574 @default.
- W2940455811 hasRelatedWork W2366184931 @default.
- W2940455811 hasRelatedWork W2371596265 @default.
- W2940455811 hasRelatedWork W2375478301 @default.
- W2940455811 hasRelatedWork W2376256034 @default.
- W2940455811 hasRelatedWork W2386751802 @default.
- W2940455811 hasRelatedWork W2418166725 @default.
- W2940455811 hasVolume "18" @default.
- W2940455811 isParatext "false" @default.
- W2940455811 isRetracted "false" @default.
- W2940455811 magId "2940455811" @default.
- W2940455811 workType "article" @default.