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- W2940589045 abstract "AT13387 is an orally bioavailable clinical candidate developed to inhibit theheat shock protein 90 (Hsp90). This article describes a modified synthetic route for the multi-gram production of AT13387 in 46% overall yield. The modified synthetic route is short, avoids stringent reaction conditions and difficult purifications, which led to increase in an overall yield." @default.
- W2940589045 created "2019-05-03" @default.
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- W2940589045 date "2019-04-23" @default.
- W2940589045 modified "2023-09-26" @default.
- W2940589045 title "The succinct synthesis of AT13387, a clinically relevant Hsp90 inhibitor" @default.
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- W2940589045 doi "https://doi.org/10.1080/00397911.2019.1602654" @default.
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