Matches in SemOpenAlex for { <https://semopenalex.org/work/W2940691141> ?p ?o ?g. }
- W2940691141 endingPage "17" @default.
- W2940691141 startingPage "5" @default.
- W2940691141 abstract "Epiblast stem cells (EpiSCs) are pluripotent cells that are derived from mouse embryos at gastrulation stages. They represent the primed state of pluripotency, in which cells are on the verge of differentiation and already express markers of the three primary lineages (mesoderm, endoderm, neurectoderm). EpiSCs display some heterogeneity intra- and inter-cell lines in the expression of some of these lineage markers. We relate this heterogeneity to signalling pathways that are active in EpiSCs, either due to addition of growth factors (FGF2 and activin) in the culture medium, or endogenously active (FGF, Nodal, and Wnt). By modulating Wnt or activin/nodal pathways, cell lines close to EpiSCs but with different properties can be obtained. These signalling pathways are all at work in vivo to pattern the pluripotent epiblast and specify cellular fates." @default.
- W2940691141 created "2019-05-03" @default.
- W2940691141 creator A5011273112 @default.
- W2940691141 date "2019-01-01" @default.
- W2940691141 modified "2023-09-25" @default.
- W2940691141 title "Heterogeneity in Epiblast Stem Cells" @default.
- W2940691141 cites W1541821200 @default.
- W2940691141 cites W1828975488 @default.
- W2940691141 cites W1829700783 @default.
- W2940691141 cites W1971012578 @default.
- W2940691141 cites W1973387539 @default.
- W2940691141 cites W1974775907 @default.
- W2940691141 cites W1977376400 @default.
- W2940691141 cites W1988397986 @default.
- W2940691141 cites W1990180850 @default.
- W2940691141 cites W1994596013 @default.
- W2940691141 cites W1998317358 @default.
- W2940691141 cites W1998841413 @default.
- W2940691141 cites W2005617468 @default.
- W2940691141 cites W2018744859 @default.
- W2940691141 cites W2018765068 @default.
- W2940691141 cites W2027310534 @default.
- W2940691141 cites W2036324628 @default.
- W2940691141 cites W2041573813 @default.
- W2940691141 cites W2055230542 @default.
- W2940691141 cites W2055570171 @default.
- W2940691141 cites W2059528261 @default.
- W2940691141 cites W2069693786 @default.
- W2940691141 cites W2070700342 @default.
- W2940691141 cites W2077683857 @default.
- W2940691141 cites W2083012260 @default.
- W2940691141 cites W2090260381 @default.
- W2940691141 cites W2105241566 @default.
- W2940691141 cites W2105427659 @default.
- W2940691141 cites W2116870178 @default.
- W2940691141 cites W2127522049 @default.
- W2940691141 cites W2142482111 @default.
- W2940691141 cites W2142514820 @default.
- W2940691141 cites W2142594935 @default.
- W2940691141 cites W2146447597 @default.
- W2940691141 cites W2158544588 @default.
- W2940691141 cites W2161604785 @default.
- W2940691141 cites W2171109270 @default.
- W2940691141 cites W2172111284 @default.
- W2940691141 cites W2255144770 @default.
- W2940691141 cites W2274491524 @default.
- W2940691141 cites W2306104084 @default.
- W2940691141 cites W2334056159 @default.
- W2940691141 cites W2339231246 @default.
- W2940691141 cites W2396711649 @default.
- W2940691141 cites W2471417487 @default.
- W2940691141 cites W2517993048 @default.
- W2940691141 cites W2520991658 @default.
- W2940691141 cites W2583932040 @default.
- W2940691141 cites W2610019744 @default.
- W2940691141 cites W2741536364 @default.
- W2940691141 cites W2774946861 @default.
- W2940691141 cites W2786431878 @default.
- W2940691141 cites W2796750766 @default.
- W2940691141 cites W2801872537 @default.
- W2940691141 cites W2806541863 @default.
- W2940691141 cites W2810466533 @default.
- W2940691141 cites W4376453756 @default.
- W2940691141 doi "https://doi.org/10.1007/978-3-030-11096-3_2" @default.
- W2940691141 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31016592" @default.
- W2940691141 hasPublicationYear "2019" @default.
- W2940691141 type Work @default.
- W2940691141 sameAs 2940691141 @default.
- W2940691141 citedByCount "3" @default.
- W2940691141 countsByYear W29406911412021 @default.
- W2940691141 countsByYear W29406911412022 @default.
- W2940691141 crossrefType "book-chapter" @default.
- W2940691141 hasAuthorship W2940691141A5011273112 @default.
- W2940691141 hasConcept C104317684 @default.
- W2940691141 hasConcept C107459253 @default.
- W2940691141 hasConcept C129536746 @default.
- W2940691141 hasConcept C137620995 @default.
- W2940691141 hasConcept C145103041 @default.
- W2940691141 hasConcept C148738053 @default.
- W2940691141 hasConcept C18155467 @default.
- W2940691141 hasConcept C196843134 @default.
- W2940691141 hasConcept C205583638 @default.
- W2940691141 hasConcept C2777164004 @default.
- W2940691141 hasConcept C2780915607 @default.
- W2940691141 hasConcept C28328180 @default.
- W2940691141 hasConcept C54355233 @default.
- W2940691141 hasConcept C62478195 @default.
- W2940691141 hasConcept C75059768 @default.
- W2940691141 hasConcept C83330619 @default.
- W2940691141 hasConcept C86803240 @default.
- W2940691141 hasConcept C87073359 @default.
- W2940691141 hasConcept C95444343 @default.
- W2940691141 hasConceptScore W2940691141C104317684 @default.
- W2940691141 hasConceptScore W2940691141C107459253 @default.
- W2940691141 hasConceptScore W2940691141C129536746 @default.
- W2940691141 hasConceptScore W2940691141C137620995 @default.
- W2940691141 hasConceptScore W2940691141C145103041 @default.
- W2940691141 hasConceptScore W2940691141C148738053 @default.