Matches in SemOpenAlex for { <https://semopenalex.org/work/W2940695792> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2940695792 endingPage "103950" @default.
- W2940695792 startingPage "103950" @default.
- W2940695792 abstract "In adult mammals, retinal ganglion cells (RGCs) fail to regenerate following damage. As a result, RGCs die after acute injury and in progressive degenerative diseases such as glaucoma; this can lead to permanent vision loss and, eventually, blindness. Lipids are crucial for the development and maintenance of cell membranes, myelin sheaths, and cellular signaling pathways, however, little is known about their role in axon injury and repair. Studies examining changes to the lipidome during optic nerve (ON) regeneration could greatly inform treatment strategies, yet these are largely lacking. Experimental animal models of ON regeneration have facilitated the exploration of the molecular determinants that affect RGC axon regeneration. Here, we analyzed lipid profiles of the ON and retina in an ON crush rat model using liquid chromatography–mass spectrometry. Furthermore, we investigated lipidome changes after ON crush followed by intravitreal treatment with Zymosan, a yeast cell wall derivative known to enhance RGC regeneration. This data is available at the NIH Common Fund's Metabolomics Data Repository and Coordinating Center (supported by NIH grant, U01-DK097430) website, the Metabolomics Workbench, http://www.metabolomicsworkbench.org, where it has been assigned Project ID: PR000661. The data can be accessed directly via it's Project DOI: doi: 10.21,228/M87D53." @default.
- W2940695792 created "2019-05-03" @default.
- W2940695792 creator A5013992450 @default.
- W2940695792 creator A5035868495 @default.
- W2940695792 creator A5040044859 @default.
- W2940695792 creator A5067107146 @default.
- W2940695792 creator A5084283166 @default.
- W2940695792 creator A5085793197 @default.
- W2940695792 date "2019-06-01" @default.
- W2940695792 modified "2023-10-17" @default.
- W2940695792 title "Comparative lipid profiling dataset of the inflammation-induced optic nerve regeneration" @default.
- W2940695792 cites W1970174386 @default.
- W2940695792 cites W2025701648 @default.
- W2940695792 cites W2060808339 @default.
- W2940695792 cites W2135551394 @default.
- W2940695792 cites W2783233668 @default.
- W2940695792 doi "https://doi.org/10.1016/j.dib.2019.103950" @default.
- W2940695792 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6517575" @default.
- W2940695792 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31193141" @default.
- W2940695792 hasPublicationYear "2019" @default.
- W2940695792 type Work @default.
- W2940695792 sameAs 2940695792 @default.
- W2940695792 citedByCount "11" @default.
- W2940695792 countsByYear W29406957922020 @default.
- W2940695792 countsByYear W29406957922021 @default.
- W2940695792 countsByYear W29406957922022 @default.
- W2940695792 countsByYear W29406957922023 @default.
- W2940695792 crossrefType "journal-article" @default.
- W2940695792 hasAuthorship W2940695792A5013992450 @default.
- W2940695792 hasAuthorship W2940695792A5035868495 @default.
- W2940695792 hasAuthorship W2940695792A5040044859 @default.
- W2940695792 hasAuthorship W2940695792A5067107146 @default.
- W2940695792 hasAuthorship W2940695792A5084283166 @default.
- W2940695792 hasAuthorship W2940695792A5085793197 @default.
- W2940695792 hasBestOaLocation W29406957921 @default.
- W2940695792 hasConcept C169760540 @default.
- W2940695792 hasConcept C171056886 @default.
- W2940695792 hasConcept C21565614 @default.
- W2940695792 hasConcept C2777093970 @default.
- W2940695792 hasConcept C2777624874 @default.
- W2940695792 hasConcept C2779530196 @default.
- W2940695792 hasConcept C2780241833 @default.
- W2940695792 hasConcept C2780837183 @default.
- W2940695792 hasConcept C58017582 @default.
- W2940695792 hasConcept C60644358 @default.
- W2940695792 hasConcept C86803240 @default.
- W2940695792 hasConcept C95444343 @default.
- W2940695792 hasConceptScore W2940695792C169760540 @default.
- W2940695792 hasConceptScore W2940695792C171056886 @default.
- W2940695792 hasConceptScore W2940695792C21565614 @default.
- W2940695792 hasConceptScore W2940695792C2777093970 @default.
- W2940695792 hasConceptScore W2940695792C2777624874 @default.
- W2940695792 hasConceptScore W2940695792C2779530196 @default.
- W2940695792 hasConceptScore W2940695792C2780241833 @default.
- W2940695792 hasConceptScore W2940695792C2780837183 @default.
- W2940695792 hasConceptScore W2940695792C58017582 @default.
- W2940695792 hasConceptScore W2940695792C60644358 @default.
- W2940695792 hasConceptScore W2940695792C86803240 @default.
- W2940695792 hasConceptScore W2940695792C95444343 @default.
- W2940695792 hasFunder F4320306078 @default.
- W2940695792 hasFunder F4320337350 @default.
- W2940695792 hasLocation W29406957921 @default.
- W2940695792 hasLocation W29406957922 @default.
- W2940695792 hasLocation W29406957923 @default.
- W2940695792 hasLocation W29406957924 @default.
- W2940695792 hasLocation W29406957925 @default.
- W2940695792 hasLocation W29406957926 @default.
- W2940695792 hasOpenAccess W2940695792 @default.
- W2940695792 hasPrimaryLocation W29406957921 @default.
- W2940695792 hasRelatedWork W1988727893 @default.
- W2940695792 hasRelatedWork W2093629098 @default.
- W2940695792 hasRelatedWork W2732317838 @default.
- W2940695792 hasRelatedWork W2746999282 @default.
- W2940695792 hasRelatedWork W2768723747 @default.
- W2940695792 hasRelatedWork W2810768141 @default.
- W2940695792 hasRelatedWork W2986402841 @default.
- W2940695792 hasRelatedWork W3207725197 @default.
- W2940695792 hasRelatedWork W3209610556 @default.
- W2940695792 hasRelatedWork W4317479263 @default.
- W2940695792 hasVolume "24" @default.
- W2940695792 isParatext "false" @default.
- W2940695792 isRetracted "false" @default.
- W2940695792 magId "2940695792" @default.
- W2940695792 workType "article" @default.