Matches in SemOpenAlex for { <https://semopenalex.org/work/W2940808320> ?p ?o ?g. }
- W2940808320 endingPage "5551" @default.
- W2940808320 startingPage "5544" @default.
- W2940808320 abstract "The purpose of the study was to investigate the transepithelial transport route of Arg-Leu-Ser-Phe-Asn-Pro (RLSFNP), a milk-derived angiotensin-converting enzyme (ACE) inhibitory peptide, and to encapsulate RLSFNP in a liposome to improve its intestinal bioavailability. The transport route was investigated using transport inhibitors in a human intestinal Caco-2 cell monolayer model. Sodium azide and wortmannin significantly reduced the permeability of RLSFNP (P < 0.01), indicating that energy-dependent transcytosis is involved in the transport of RLSFNP across Caco-2 cells. The hexapeptide RLSFNP was then embedded in liposomes, and the RLSFNP liposome was characterized. Afterward, the cellular uptake and transepithelial transport ability of the RLSFNP liposome across Caco-2 cell monolayers was observed. The results demonstrated that the RLSFNP liposome was successfully prepared, having a significant sustained release and storage capability. The RLSFNP liposome can be absorbed by Caco-2 cells, with an increased intestinal absorption of RLSFNP compared to RLSFNP alone. The results showed a new way to improve RLSFNP intestinal bioavailability." @default.
- W2940808320 created "2019-05-03" @default.
- W2940808320 creator A5035701638 @default.
- W2940808320 creator A5049889863 @default.
- W2940808320 creator A5050745133 @default.
- W2940808320 creator A5060259824 @default.
- W2940808320 creator A5060941170 @default.
- W2940808320 creator A5068741303 @default.
- W2940808320 creator A5083956383 @default.
- W2940808320 creator A5085201377 @default.
- W2940808320 creator A5090547325 @default.
- W2940808320 date "2019-04-22" @default.
- W2940808320 modified "2023-10-17" @default.
- W2940808320 title "Transepithelial Transport Route and Liposome Encapsulation of Milk-Derived ACE-Inhibitory Peptide Arg-Leu-Ser-Phe-Asn-Pro" @default.
- W2940808320 cites W172337120 @default.
- W2940808320 cites W197645179 @default.
- W2940808320 cites W1984153473 @default.
- W2940808320 cites W1988193392 @default.
- W2940808320 cites W2008173042 @default.
- W2940808320 cites W2010783504 @default.
- W2940808320 cites W2038781257 @default.
- W2940808320 cites W2039482441 @default.
- W2940808320 cites W2048654159 @default.
- W2940808320 cites W2061510929 @default.
- W2940808320 cites W2070296002 @default.
- W2940808320 cites W2079769017 @default.
- W2940808320 cites W2085937524 @default.
- W2940808320 cites W2121013822 @default.
- W2940808320 cites W2125012638 @default.
- W2940808320 cites W2128107708 @default.
- W2940808320 cites W2138284504 @default.
- W2940808320 cites W2142380191 @default.
- W2940808320 cites W2142596415 @default.
- W2940808320 cites W2154555351 @default.
- W2940808320 cites W2168163081 @default.
- W2940808320 cites W2228216144 @default.
- W2940808320 cites W2321629193 @default.
- W2940808320 cites W2333604692 @default.
- W2940808320 cites W2398752419 @default.
- W2940808320 cites W2514009785 @default.
- W2940808320 cites W2518784592 @default.
- W2940808320 cites W2581569087 @default.
- W2940808320 cites W2591341230 @default.
- W2940808320 cites W2594531952 @default.
- W2940808320 cites W2717939678 @default.
- W2940808320 cites W2735303589 @default.
- W2940808320 cites W2782020873 @default.
- W2940808320 cites W2792141492 @default.
- W2940808320 cites W2801891672 @default.
- W2940808320 cites W282448408 @default.
- W2940808320 cites W803825273 @default.
- W2940808320 doi "https://doi.org/10.1021/acs.jafc.9b00397" @default.
- W2940808320 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31007021" @default.
- W2940808320 hasPublicationYear "2019" @default.
- W2940808320 type Work @default.
- W2940808320 sameAs 2940808320 @default.
- W2940808320 citedByCount "30" @default.
- W2940808320 countsByYear W29408083202019 @default.
- W2940808320 countsByYear W29408083202020 @default.
- W2940808320 countsByYear W29408083202021 @default.
- W2940808320 countsByYear W29408083202022 @default.
- W2940808320 countsByYear W29408083202023 @default.
- W2940808320 crossrefType "journal-article" @default.
- W2940808320 hasAuthorship W2940808320A5035701638 @default.
- W2940808320 hasAuthorship W2940808320A5049889863 @default.
- W2940808320 hasAuthorship W2940808320A5050745133 @default.
- W2940808320 hasAuthorship W2940808320A5060259824 @default.
- W2940808320 hasAuthorship W2940808320A5060941170 @default.
- W2940808320 hasAuthorship W2940808320A5068741303 @default.
- W2940808320 hasAuthorship W2940808320A5083956383 @default.
- W2940808320 hasAuthorship W2940808320A5085201377 @default.
- W2940808320 hasAuthorship W2940808320A5090547325 @default.
- W2940808320 hasConcept C12554922 @default.
- W2940808320 hasConcept C1491633281 @default.
- W2940808320 hasConcept C181389837 @default.
- W2940808320 hasConcept C185154212 @default.
- W2940808320 hasConcept C185350488 @default.
- W2940808320 hasConcept C185592680 @default.
- W2940808320 hasConcept C193176779 @default.
- W2940808320 hasConcept C2776929087 @default.
- W2940808320 hasConcept C2779281246 @default.
- W2940808320 hasConcept C2781417787 @default.
- W2940808320 hasConcept C28005876 @default.
- W2940808320 hasConcept C55493867 @default.
- W2940808320 hasConcept C86803240 @default.
- W2940808320 hasConcept C98274493 @default.
- W2940808320 hasConceptScore W2940808320C12554922 @default.
- W2940808320 hasConceptScore W2940808320C1491633281 @default.
- W2940808320 hasConceptScore W2940808320C181389837 @default.
- W2940808320 hasConceptScore W2940808320C185154212 @default.
- W2940808320 hasConceptScore W2940808320C185350488 @default.
- W2940808320 hasConceptScore W2940808320C185592680 @default.
- W2940808320 hasConceptScore W2940808320C193176779 @default.
- W2940808320 hasConceptScore W2940808320C2776929087 @default.
- W2940808320 hasConceptScore W2940808320C2779281246 @default.
- W2940808320 hasConceptScore W2940808320C2781417787 @default.
- W2940808320 hasConceptScore W2940808320C28005876 @default.
- W2940808320 hasConceptScore W2940808320C55493867 @default.