FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2941053112> ?p ?o ?g. }

• W2941053112 endingPage "1251" @default.
• W2941053112 startingPage "1240" @default.
• W2941053112 abstract "Agents capable of scavenging ROS have attracted attention recently because of their potential use as antioxidative agents. Amifostine, a ROS scavenger, has the potential to be used as an antioxidant in therapeutic applications. In this study, the effect of amifostine on neutral zwitterionic dipalmitoylphosphatidylcholine (DPPC) and anionic dipalmitoylphosphatidylglycerol (DPPG) model membranes' structure and dynamics is aimed to be examined by Fourier transform infrared (FTIR) spectroscopy and differential scanning calorimetry (DSC). Our results revealed that amifostine at concentrations used (1-24 mol%) does not induce any important alteration in the shape of phase transition curve and phase transition temperature in the DPPC and DPPG membranes. High concentrations of amifostine slightly increased the acyl chain flexibility of DPPC membranes in the liquid crystalline phase and DPPG membranes in the gel phase. A lessening in the dynamics of DPPC liposomes was observed for all concentrations of amifostine in both phases but slight dual effect was observed only in the gel phase as a decrease in dynamics at low concentrations and an increase at higher concentrations of amifostine in DPPG liposomes. Additionally, strong hydrogen bonding was observed for both CO and PO2- groups in case of DPPC and for PO2- groups in case of DPPG. Dehydration around the CO regions occurred in case of DPPG. Accordingly, amifostine is proposed to be interacting strongly with zwitterionic and negatively charged membrane head groups and glycerol backbone in all concentrations and because of this interaction it causes some changes in lipid order and dynamics especially at high concentrations." @default.
• W2941053112 created "2019-05-03" @default.
• W2941053112 creator A5015314873 @default.
• W2941053112 creator A5020259269 @default.
• W2941053112 date "2019-06-01" @default.
• W2941053112 modified "2023-09-26" @default.
• W2941053112 title "The effects of radioprotectant and potential antioxidant agent amifostine on the structure and dynamics of DPPC and DPPG liposomes" @default.
• W2941053112 cites W1976561097 @default.
• W2941053112 cites W1978424085 @default.
• W2941053112 cites W1979858307 @default.
• W2941053112 cites W1982640374 @default.
• W2941053112 cites W1991442336 @default.
• W2941053112 cites W1997476000 @default.
• W2941053112 cites W2008315798 @default.
• W2941053112 cites W2015060049 @default.
• W2941053112 cites W2017920450 @default.
• W2941053112 cites W2025307517 @default.
• W2941053112 cites W2025809965 @default.
• W2941053112 cites W2033198837 @default.
• W2941053112 cites W2035772360 @default.
• W2941053112 cites W2036375437 @default.
• W2941053112 cites W2038452544 @default.
• W2941053112 cites W2040672621 @default.
• W2941053112 cites W2041274632 @default.
• W2941053112 cites W2042870644 @default.
• W2941053112 cites W2043508204 @default.
• W2941053112 cites W2045861480 @default.
• W2941053112 cites W2049881160 @default.
• W2941053112 cites W2050629200 @default.
• W2941053112 cites W2053999202 @default.
• W2941053112 cites W2054873632 @default.
• W2941053112 cites W2055721250 @default.
• W2941053112 cites W2057323378 @default.
• W2941053112 cites W2060058925 @default.
• W2941053112 cites W2060467802 @default.
• W2941053112 cites W2061593573 @default.
• W2941053112 cites W2063970243 @default.
• W2941053112 cites W2065150817 @default.
• W2941053112 cites W2067577502 @default.
• W2941053112 cites W2067578000 @default.
• W2941053112 cites W2067953558 @default.
• W2941053112 cites W2068991920 @default.
• W2941053112 cites W2077031396 @default.
• W2941053112 cites W2077651669 @default.
• W2941053112 cites W2079723976 @default.
• W2941053112 cites W2082537826 @default.
• W2941053112 cites W2085461619 @default.
• W2941053112 cites W2087691890 @default.
• W2941053112 cites W2088342708 @default.
• W2941053112 cites W2089232423 @default.
• W2941053112 cites W2090481539 @default.
• W2941053112 cites W2090900051 @default.
• W2941053112 cites W2091738176 @default.
• W2941053112 cites W2092685208 @default.
• W2941053112 cites W2094028885 @default.
• W2941053112 cites W209924246 @default.
• W2941053112 cites W2104179452 @default.
• W2941053112 cites W2109007802 @default.
• W2941053112 cites W2109618659 @default.
• W2941053112 cites W2112014931 @default.
• W2941053112 cites W2120993694 @default.
• W2941053112 cites W2126982708 @default.
• W2941053112 cites W2167621672 @default.
• W2941053112 cites W2297773874 @default.
• W2941053112 cites W2314498731 @default.
• W2941053112 cites W2326438433 @default.
• W2941053112 cites W2332946017 @default.
• W2941053112 cites W2510766822 @default.
• W2941053112 cites W2913059889 @default.
• W2941053112 doi "https://doi.org/10.1016/j.bbamem.2019.04.009" @default.
• W2941053112 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31028720" @default.
• W2941053112 hasPublicationYear "2019" @default.
• W2941053112 type Work @default.
• W2941053112 sameAs 2941053112 @default.
• W2941053112 citedByCount "15" @default.
• W2941053112 countsByYear W29410531122019 @default.
• W2941053112 countsByYear W29410531122020 @default.
• W2941053112 countsByYear W29410531122021 @default.
• W2941053112 countsByYear W29410531122022 @default.
• W2941053112 countsByYear W29410531122023 @default.
• W2941053112 crossrefType "journal-article" @default.
• W2941053112 hasAuthorship W2941053112A5015314873 @default.
• W2941053112 hasAuthorship W2941053112A5020259269 @default.
• W2941053112 hasBestOaLocation W29410531121 @default.
• W2941053112 hasConcept C112887158 @default.
• W2941053112 hasConcept C121332964 @default.
• W2941053112 hasConcept C12554922 @default.
• W2941053112 hasConcept C127413603 @default.
• W2941053112 hasConcept C160892712 @default.
• W2941053112 hasConcept C178790620 @default.
• W2941053112 hasConcept C185154212 @default.
• W2941053112 hasConcept C185592680 @default.
• W2941053112 hasConcept C2776330855 @default.
• W2941053112 hasConcept C2778004101 @default.
• W2941053112 hasConcept C2778918659 @default.
• W2941053112 hasConcept C2779387952 @default.
• W2941053112 hasConcept C2781172473 @default.
• W2941053112 hasConcept C29730261 @default.

• next