FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2941124580> ?p ?o ?g. }

• W2941124580 abstract "Abstract Single-cell whole-genome sequencing (scWGS) is mainly used to probe intercellular genomic variations, focusing on the copy number variations or alterations and the single-nucleotide variations (SNVs) occurring within single cells. Single-cell whole-genome amplification (scWGA) needs to be applied before scWGS but is challenging due to the low copy number of DNA. Besides, many genomic variations are rare within a population of cells, so the throughput of currently available scWGA methods is far from satisfactory. Here, we integrate a one-step micro-capillary array (MiCA)-based centrifugal droplet generation technique with emulsion multiple displacement amplification (eMDA) and demonstrate a high-throughput scWGA method, MiCA-eMDA. MiCA-eMDA increases the single-run throughput of scWGA to a few dozen, and enables the assessment of copy number variations and alterations at 50-kb resolution. Downstream target enrichment further enables the detection of SNVs with 20% allele drop-out." @default.
• W2941124580 created "2019-05-03" @default.
• W2941124580 creator A5002699363 @default.
• W2941124580 creator A5007846432 @default.
• W2941124580 creator A5008885756 @default.
• W2941124580 creator A5009781116 @default.
• W2941124580 creator A5035554886 @default.
• W2941124580 creator A5057539340 @default.
• W2941124580 creator A5068252474 @default.
• W2941124580 creator A5075382734 @default.
• W2941124580 creator A5078682047 @default.
• W2941124580 creator A5079605407 @default.
• W2941124580 date "2019-04-29" @default.
• W2941124580 modified "2023-10-16" @default.
• W2941124580 title "High-throughput single-cell whole-genome amplification through centrifugal emulsification and eMDA" @default.
• W2941124580 cites W1602702667 @default.
• W2941124580 cites W1841351562 @default.
• W2941124580 cites W1968762427 @default.
• W2941124580 cites W1974113747 @default.
• W2941124580 cites W1984731778 @default.
• W2941124580 cites W1986944049 @default.
• W2941124580 cites W2004232113 @default.
• W2941124580 cites W2008628868 @default.
• W2941124580 cites W2023887100 @default.
• W2941124580 cites W2032518018 @default.
• W2941124580 cites W2064977507 @default.
• W2941124580 cites W2065340354 @default.
• W2941124580 cites W2068674866 @default.
• W2941124580 cites W2068881679 @default.
• W2941124580 cites W2071010503 @default.
• W2941124580 cites W2075691559 @default.
• W2941124580 cites W2086277161 @default.
• W2941124580 cites W2088470456 @default.
• W2941124580 cites W2090461073 @default.
• W2941124580 cites W2103441770 @default.
• W2941124580 cites W2105970624 @default.
• W2941124580 cites W2107680358 @default.
• W2941124580 cites W2111747321 @default.
• W2941124580 cites W2119180969 @default.
• W2941124580 cites W2129288227 @default.
• W2941124580 cites W2136680615 @default.
• W2941124580 cites W2154068087 @default.
• W2941124580 cites W2170551349 @default.
• W2941124580 cites W2286667211 @default.
• W2941124580 cites W2332292689 @default.
• W2941124580 cites W2498989218 @default.
• W2941124580 cites W2528280327 @default.
• W2941124580 cites W2546514099 @default.
• W2941124580 cites W2560012560 @default.
• W2941124580 cites W2580989000 @default.
• W2941124580 cites W2605512081 @default.
• W2941124580 cites W2626695356 @default.
• W2941124580 cites W2736547131 @default.
• W2941124580 cites W4247053599 @default.
• W2941124580 doi "https://doi.org/10.1038/s42003-019-0401-y" @default.
• W2941124580 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6488574" @default.
• W2941124580 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31044172" @default.
• W2941124580 hasPublicationYear "2019" @default.
• W2941124580 type Work @default.
• W2941124580 sameAs 2941124580 @default.
• W2941124580 citedByCount "33" @default.
• W2941124580 countsByYear W29411245802019 @default.
• W2941124580 countsByYear W29411245802020 @default.
• W2941124580 countsByYear W29411245802021 @default.
• W2941124580 countsByYear W29411245802022 @default.
• W2941124580 countsByYear W29411245802023 @default.
• W2941124580 crossrefType "journal-article" @default.
• W2941124580 hasAuthorship W2941124580A5002699363 @default.
• W2941124580 hasAuthorship W2941124580A5007846432 @default.
• W2941124580 hasAuthorship W2941124580A5008885756 @default.
• W2941124580 hasAuthorship W2941124580A5009781116 @default.
• W2941124580 hasAuthorship W2941124580A5035554886 @default.
• W2941124580 hasAuthorship W2941124580A5057539340 @default.
• W2941124580 hasAuthorship W2941124580A5068252474 @default.
• W2941124580 hasAuthorship W2941124580A5075382734 @default.
• W2941124580 hasAuthorship W2941124580A5078682047 @default.
• W2941124580 hasAuthorship W2941124580A5079605407 @default.
• W2941124580 hasBestOaLocation W29411245801 @default.
• W2941124580 hasConcept C104317684 @default.
• W2941124580 hasConcept C120821319 @default.
• W2941124580 hasConcept C141231307 @default.
• W2941124580 hasConcept C144024400 @default.
• W2941124580 hasConcept C149923435 @default.
• W2941124580 hasConcept C156385826 @default.
• W2941124580 hasConcept C157764524 @default.
• W2941124580 hasConcept C16671776 @default.
• W2941124580 hasConcept C174749747 @default.
• W2941124580 hasConcept C2908647359 @default.
• W2941124580 hasConcept C41008148 @default.
• W2941124580 hasConcept C49105822 @default.
• W2941124580 hasConcept C501734568 @default.
• W2941124580 hasConcept C51679486 @default.
• W2941124580 hasConcept C54355233 @default.
• W2941124580 hasConcept C552990157 @default.
• W2941124580 hasConcept C555944384 @default.
• W2941124580 hasConcept C70721500 @default.
• W2941124580 hasConcept C76155785 @default.
• W2941124580 hasConcept C78063203 @default.
• W2941124580 hasConcept C86803240 @default.
• W2941124580 hasConceptScore W2941124580C104317684 @default.

• next