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- W2941134134 endingPage "209" @default.
- W2941134134 startingPage "201" @default.
- W2941134134 abstract "Triclocarban (TCC) is considered as contaminant of emerging concern (CEC), and ranked in the top 10 CEC occurrence. TCC is a high production volume synthetic chemical used extensively in various personal care products. This chemical will be released into the environment via incomplete wastewater treatment and untreated wastewater discharge. TCC and its transformation products (4,4'-dichlorocarbilide (DCC),1-(3-chlorophenyl)-3-phenylurea (MCC) and carbanilide (NCC),2'OH-TCC, 3'OH-TCC) were detected in the environmental matrices. Sediment organic carbon will influence TCC concentrations in suspended and bed sediments. TCC is an antimicrobial agent and also emerging endocrine disruptor that can cause immune dysfunction and affect human reproductive outcomes. Furthermore, TCC alters the expression of proteins related to binding and metabolism, skeletal muscle development and function, nervous system development and immune response. TCC has potential health risks in wildlife and humans. Several animal studies illustrate that it can cause various adverse effects, which can be monitored by antioxidant biomarkers (CAT, GST and LPO). Accumulation of TCC in organisms depends on the lipophilicity and bioavailability of TCC in sediment and water. TCC was continuously detected in aquatic system. TCC is a lipophilic compound, which can efficiently bind with lipid content. Women are more vulnerable to TCC due to substantially higher frequency and extended exposure to TCC. This review provides basic information of occurrence of TCC and the exposure levels in aquatic organisms. Several literature have shown the higher usage and human exposure levels of TCC, which provides useful information for the chemical management approaches." @default.
- W2941134134 created "2019-05-03" @default.
- W2941134134 creator A5041153512 @default.
- W2941134134 creator A5060225029 @default.
- W2941134134 creator A5090003924 @default.
- W2941134134 date "2019-09-01" @default.
- W2941134134 modified "2023-10-14" @default.
- W2941134134 title "Fate of Triclocarban (TCC) in aquatic and terrestrial systems and human exposure" @default.
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