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- W2941153012 abstract "目的比较永久、可降解及无聚合物涂层3种支架治疗无保护左主干病变的安全性及有效性。 方法本研究纳入了2013年1月-2017年6月于陆军军医大学(第三军医大学)第二附属医院心血管内科经冠状动脉造影诊断为冠状动脉无保护左主干病变，并行支架植入术的患者共259例，按照左主干植入支架的不同分为永久性聚合物涂层支架组(PP-DES, n=153)、可降解聚合物涂层支架组(BP-DES, n=54)和无聚合物涂层支架组(PF-DES, n=52)，随访至术后12个月，比较3组患者支架植入术后12个月内靶血管失败(心源性死亡、靶血管相关性心肌梗死、靶血管再次血运重建)和主要心血管不良事件(心源性死亡、非致死性心肌梗死、再次血运重建)的发生情况。 结果3组患者在性别、年龄、临床诊断、合并高危因素及病变类型、支架术式、真性分叉病变比例等方面的差异无统计学意义(P>0.05)，术后12个月内靶血管失败(P=0.596)及主要心血管不良事件发生率差异无统计学意义(P=0.210)。多因素COX回归分析显示:支架类型与患者术后12个月内发生靶血管失败及主要心血管不良事件无显著相关性(P>0.05)。 结论可降解聚合物涂层支架、无聚合物涂层支架治疗无保护左主干病变的靶血管失败及主要心血管不良事件发生率与永久性聚合物涂层支架相当，这两种新型支架治疗无保护左主干病变安全有效。" @default.
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- W2941153012 date "2019-03-01" @default.
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- W2941153012 title "Clinical analysis of permanent, biodegradable and polymer-free drug eluting stent in treatment of unprotected left main coronary artery disease" @default.
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