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- W2941161520 abstract "// Ming Li 1 , Ying Wang 2, 3 , Liang Cheng 4 , Wanting Niu 5 , Guoan Zhao 6 , Jithin K. Raju 7 , Jun Huo 1 , Bin Wu 1 , Bo Yin 1 , Yongsheng Song 1 and Renge Bu 1 1 Department of Urology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China 2 Department of Nuclear Medicine, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, P.R. China 3 Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA 4 Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA 5 Department of Orthopedics, Brigham and Women’s Hospital, VA Boston Healthcare System, Harvard Medical School, Boston, Massachusetts 02115, USA 6 School of Network Education, Beijing University of Posts and Telecommunications, Hebei, Beijing 100088, P.R. China 7 Department of Clinical Medicine, China Medical University, Shenyang, Liaoning 110122, P.R. China Correspondence to: Renge Bu, email: burg@sj-hospital.org Keywords: renal cell carcinoma, lncRNA, diagnosis, prognosis, therapy Received: November 18, 2016 Accepted: March 20, 2017 Published: April 12, 2017 ABSTRACT Renal cell carcinoma is one of the most common malignancy in adults, its prognosis is poor in an advanced stage and early detection is difficult due to the lack of molecular biomarkers. The identification of novel biomarkers for RCC is an urgent and meaningful project. Long non-coding RNA (lncRNA) is transcribed from genomic regions with a minimum length of 200 bases and limited protein-coding potential. Recently, lncRNAs have been greatly studied in a variety of cancer types. They participate in a wide variety of biological processes including cancer biology. In this review, we provide a new insight of the profiling of lncRNAs in RCC and their roles in renal carcinogenesis, with an emphasize on their potential in diagnosis, prognosis and potential roles in RCC therapy." @default.
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- W2941161520 date "2017-04-12" @default.
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- W2941161520 title "Long non-coding RNAs in renal cell carcinoma: A systematic review and clinical implications" @default.
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